Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Trimethyl Phosphite (CAS: 121-45-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Trimethyl Phosphite (CAS: 121-45-9), Please contact: alvin@ruifuchem.com
| Chemical Name | Trimethyl Phosphite |
| Synonyms | P(OMe)3; P(OCH3)3; Trimethylphosphite; Trimethoxyphosphine; Phosphorous Acid Trimethyl Ester; Trimethyl Ester Phosphorous Acid; Methyl Phosphite |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 121-45-9 |
| Molecular Formula | C3H9O3P |
| Molecular Weight | 124.08 g/mol |
| Melting Point | -78℃(lit.) |
| Boiling Point | 111.0~112.0℃(lit.) |
| Flash Point | 28℃ |
| Density | 1.052 g/mL at 25℃(lit.) |
| Refractive Index n20/D | 1.408(lit.) |
| Sensitive | Air Sensitive, Moisture Sensitive. Store Under Inert Gas |
| Water Solubility | Hydrolyzes with Water |
| Solubility | Very Soluble in Ether, Ethanol |
| Hazard Class | 3; Flammable Liquid |
| Packing Group | III |
| COA & MSDS | Available |
| Sample | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Colorless Liquid | Colorless Liquid |
| Purity / Analysis Method | >99.0% (GC) | 99.29% |
| Dimethyl Phosphite | <1.00% | <1.00% |
| Refractive Index n20/D | 1.407~1.409 | Complies |
| Density (20℃) | 1.051~1.053 | Complies |
| Infrared Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Air and moisture sensitive. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from air, light and moisture. Away from open flame, high temperature, and the oxidant is stored separately. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage should be protected with nitrogen to prevent automatic oxidation of Trimethyl Phosphate. According to the provisions of the storage and transportation of toxic chemicals.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R10 - Flammable
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R41 - Risk of serious damage to eyes
R37/38 - Irritating to respiratory system and skin.
R65 - Harmful: May cause lung damage if swallowed
R48/23/24/25 -
R11 - Highly Flammable
R46 - May cause heritable genetic damage
R45 - May cause cancer
R67 - Vapors may cause drowsiness and dizziness
R66 - Repeated exposure may cause skin dryness or cracking
R36 - Irritating to the eyes
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S16 - Keep away from sources of ignition.
S53 - Avoid exposure - obtain special instructions before use.
UN IDs UN 2329 3/PG 3
WGK Germany 1
RTECS TH1400000
FLUKA BRAND F CODES 10-13-21
TSCA Yes
HS Code 2920 2300.00
Hazard Class 3
Packing Group III
Toxicity LD50 orally in Rabbit: 1600 mg/kg LD50 dermal Rabbit 2600 mg/kg
Trimethyl Phosphite (CAS: 121-45-9) is a colorless liquid. Distinctive pungent, pyridine-like odor. The Odor Threshold is 0.0001 ppm. Trimethyl Phosphite has been used primarily as an intermediate in the manufacture of pesticides and the synthesis of organophosphate insecticides. It is also used as a fire retardants in the production of textiles, as an intermediate in the production of flame-retardant polymers for polyurethane foams, and as a catalyst. It is used in making pesticides, flame retardants and organophosphorous additives. And as a synthetic polymerization catalyst and coating additive.
ChEBI: Trimethyl phosphite is an organophosphorus compound that is phosphane in which the three hydrogens are replaced by methoxy groups. It is an alkylating agent used primarily in the synthesis of organophosphate compounds. It has a role as an alkylating agent.
Highly flammable. Insoluble in water and denser than water. Slowly reacts with water to form phosphoric acid and corresponding organic alcohol. Trimethyl Phosphite hydrolyzes in water to form Dimethyl Phosphite and methanol. The hydrolysis rate of Trimethyl Phosphite is expected to be similar to the hydrolysis rate of Triethyl Phosphite (SRC).
Special Hazards of Combustion Products: Toxic fumes of PO x. Flammable in open flame, high temperature, strong oxidant; thermal decomposition of toxic phosphorus oxide gas.
Moderately toxic by ingestion and skin contact. An experimental teratogen. A severe skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use water, foam, fog, CO2. Violent explosive reaction on contact with magnesium perchlorate or trimethyl platinum(IV) azide tetramer. When heated to decomposition it emits toxic fumes of POx. An intermediate in the production of pesticides, fire retardants, and organic phosphorus additives. See also ESTERS.
Vaor May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Violent reaction with magnesium perchlorate. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Reacts (hydrolyzes) with water. Incompatible with air, moisture.
UN2329 Trimethyl phosphite, Hazard Class: 3; Labels: 3-Flammable liquid.