Manufacturer Supply with High Purity and Stable Quality
Chemical Name: (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid
CAS: 75028-24-9
| Chemical Name |
(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid |
| Synonyms |
Ceftaroline Fosamil 7-Position Side Chain; ATDE |
| CAS Number |
75028-24-9 |
| CAT Number |
RF-PI559 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C6H8N4O3S |
| Molecular Weight |
216.22 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Light Yellow Crystalline Powder |
| Purity / Analysis Method |
≥99.0% (HPLC) |
| Moisture (K.F) |
≤0.50% |
| Single Impurity |
≤0.50% |
| Total Impurities |
≤1.0% |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Ceftaroline Fosamil (TAK-599), a Cephalosporin derivative |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid (CAS: 75028-24-9) is an important intermediate for the preparation of Ceftaroline Fosamil (TAK-599). Ceftaroline fosamil is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Ceftaroline Fosamil is a prodrug of Ceftaroline. It is being developed by Forest Laboratories, under a license from Takeda. It received approval from the U.S. Food and Drug Administration (FDA) for the treatment of community-acquired bacterial pneumonia and acute bacterial skin infections on 29 October 2010.