Manufacturer Supply Rivaroxaban Related Intermediates:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-one CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8
Chemical Name |
(S)-(+)-Glycidyl Phthalimide |
Synonyms |
(S)-Glycidyl Phthalimide; (S)-N-Glycidylphthalimide; Rivaroxaban Intermediate |
CAS Number |
161596-47-0 |
CAT Number |
RF-PI128 |
Stock Status |
In Stock, Production Scale Up to Tons |
Molecular Formula |
C11H9NO3 |
Molecular Weight |
203.19 |
Melting Point |
102℃ |
Brand |
Ruifu Chemical |
Item |
Specifications |
Appearance |
White to Off-White Powder |
Identification |
HPLC |
Loss on Drying |
≤0.50% |
Sulphate Ash |
≤0.50% |
Purity / Analysis Method |
≥98.0% (HPLC) |
Phthalimide |
≤0.10% |
Single Max Impurity |
≤0.50% |
Total Impurities |
≤2.0% |
Epichlorohydrin |
≤0.10% |
Glycidol |
≤0.10% |
Chiral Purity |
R-isomer ≤2.0% (HPLC) |
Test Standard |
Enterprise Standard |
Usage |
Rivaroxaban (CAS: 366789-02-8) Intermediate |
(S)-(+)-Glycidyl Phthalimide CAS: 161596-47-0 Synthesis Route
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (S)-(+)-Glycidyl Phthalimide (CAS: 161596-47-0) with high quality. It is an intermediate typically in the synthesis of Rivaroxaban (CAS: 366789-02-8), in the treatment of Venous Thromboembolism (VTE).
Rivaroxaban (Xarelto; CAS: 366789-02-8) is an antithrombotic drug and was developed in a collaboration between the German Bayer Pharmaceuticals and American Johnson company. Rivaroxaban is indicated for the treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults.