Commercial Supply Tenofovir Related Intermediates:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
| Chemical Name | (R)-9-(2-Hydroxypropyl)adenine |
| Synonyms | (R)-6-Amino-9-(2-hydroxypropyl)purine |
| CAS Number | 14047-28-0 |
| CAT Number | RF-PI514 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C8H11N5O |
| Molecular Weight | 193.21 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Almost White Crystalline Powder |
| Assay / Analysis Method | ≥99.0% (HPLC) |
| Melting Point | >193℃ |
| Isomer | ≤1.0% (HPLC) |
| Loss on Drying | ≤0.50% |
| Heavy Metals (as Pb) | ≤20ppm |
| Adenine | ≤0.50% (HPLC) |
| Total Impurities | ≤1.0% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Tenofovir |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
(R)-9-(2-Hydroxypropyl)adenine (CAS: 14047-28-0) is an intermediate of Tenofovir. Tenofovir is a drug used for the treatment of chronic heptatitis B as well as prevention and treatment of HIV/AIDS. It is a kind of nucleotide analog, acting as the reverse-transcriptase inhibitor (NtRTI). It inhibits the activity of HIV reverse transcriptase through competing with the natural substrate deoxyadenosine 5’-triphosphate, causing the termination of DNA chain.