Manufacturer with High Purity and Stable Quality
Chemical Name: Zoledronic Acid Monohydrate
CAS: 165800-06-6
A highly potent bisphosphonate and activator of PKC
API High Quality, Commercial Production
| Chemical Name |
Zoledronic Acid Monohydrate |
| CAS Number |
165800-06-6 |
| CAT Number |
RF-API56 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C5H12N2O8P2 |
| Molecular Weight |
290.1 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Almost Crystalline Powder |
| Identification |
IR spectrum
HPLC chromatogram UV-Vis:
There is a maximum absorbance at 210nm |
| pH |
2.0~4.0 |
| Clarity and Color |
Comply with requirements |
| Single Impurity |
≤0.50% |
| Total Impurities |
≤1.0% |
| Loss on Drying |
5.0%~8.0% |
| Chloride |
≤0.02% |
| Phosphate |
≤0.50% |
| Phosphite |
≤0.50% |
| Heavy Metals |
≤10ppm |
| Purity |
≥99.0% |
| Test Standard |
Enterprise Standard |
| Usage |
API |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Zoledronic acid monohydrate is a highly potent bisphosphonate and activator of PKC.Zoledronic acid monohydrate is a heterocyclic bisphosphonate that is considered to have the highest potency of bisphosphonates for suppression of increased bone resorption and has been used in several osteoporosis studies. The compound has been observed to be more effective than pamidronate (sc-203178). Zoledronic acid has been used in studies investigating mesothelioma. Zoledronic acid monohydrate is an inhibitor of ASM and FDPS and an activator of PKC. Zoledronic acid (zoledronate) is a bisphosphonate bone resorption inhibitor, an inhibitor of farnesyl diphosphate (FPP) synthase which results in downstream inhibition of osteoclast activity and reduced bone resorption and turnover. It has been used to treat postmenopausal osteoporosis, Paget's disease, hypercalcemia, and along with cancer chemotherapy to treat bone damage caused by cancer that has spread to the bones.