Home Categories Send inquiry

Ethyl 4,4-Difluoroacetoacetate CAS 352-24-9 Purity >98.0% (GC)

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Ethyl 4,4-Difluoroacetoacetate (Ethyl 4,4-Difluoro-3-Oxobutanoate) (CAS: 352-24-9) with high quality.
Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Ethyl 4,4-Difluoroacetoacetate or other products, please contact us by e-mail: alvin@ruifuchem.com

Chemical Name Ethyl 4,4-Difluoroacetoacetate
Synonyms Ethyl 4,4-Difluoro-3-Oxobutanoate; Ethyl 4,4-Difluoro-3-Oxobutyrate; 4,4-Difluoro-3-Oxobutyric Acid Ethyl Ester; 4,4-Difluoroacetoacetic Acid Ethyl Ester; 4,4-Ethyl Difluoroacetoacetate
Stock Status In Stock, Commercial Production  
CAS Number 352-24-9
Molecular Formula C6H8F2O3
Molecular Weight 166.12 g/mol
Melting Point -46℃ 
Boiling Point 160℃
Flash Point 68℃ (154.4°F)
Specific Gravity (20/20)   1.23 
Refractive Index n20/D 1.40
Sensitive Heat Sensitive 
Storage Temperature Store at 0~8℃ 
Hazard Class 3; Flammable Liquid
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical
Items Specifications  Results
Appearance Colorless Liquid   Colorless Liquid  
Water by Karl Fischer  <0.50% 0.06%
Refractive Index n20/D 1.404~1.409 Conforms 
Purity / Analysis Method >98.0% (GC)  98.9%
1H NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications

Package: Fluorinated Bottle, 25kg/Drum, 200kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (0~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Risk Codes R10 - Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
R36/38 - Irritating to eyes and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs 1993
WGK Germany 3
TSCA Yes
Hazard Note Flammable
Hazard Class IRRITANT, FLAMMABLE
HS Code 2918300090

Ethyl 4,4-Difluoroacetoacetate (Ethyl 4,4-Difluoro-3-Oxobutanoate) (CAS: 352-24-9) is the active intermediate in the synthesis of pesticides, pharmaceuticals, agrochemicals and other industrial chemicals.
Ethyl 4,4-Difluoroacetoacetate has significant potential implications in various fields of research and industry. In the pharmaceutical industry, Ethyl 4,4-Difluoroacetoacetate could be used in drug development for treating cancer and other diseases. In the agrochemical industry, Ethyl 4,4-Difluoroacetoacetate could be used to develop new herbicides and pesticides. Additionally, Ethyl 4,4-Difluoroacetoacetate has potential applications in materials science, particularly in developing fluorinated polymers and surfactants.