Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Diethyl (Bromodifluoromethyl)phosphonate (CAS: 65094-22-6) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
| Chemical Name | Diethyl (Bromodifluoromethyl)phosphonate |
| Synonyms | (Bromodifluoromethyl)phosphonic Acid Diethyl Ester |
| CAS Number | 65094-22-6 |
| CAT Number | RF-PI2211 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C5H10BrF2O3P |
| Molecular Weight | 267.01 |
| Boiling Point | 102℃/16 mmHg |
| Solubility | Chloroform, Ethyl Acetate |
| Water Solubility | Not Miscible or Difficult to Mix in Water |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Colorless to Pale Yellow Liquid |
| Purity / Analysis Method | >97.0% (GC) |
| Refractive Index n20/D | 1.415~1.419 |
| Specific Gravity (20/20℃) | 1.502~1.504 |
| Water by Karl Fischer | <0.50% |
| Infrared Spectrum | Conforms to Structure |
| Proton NMR Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediates |
Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
Diethyl (Bromodifluoromethyl)phosphonate (CAS: 65094-22-6), Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis. Diethyl (Bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.