Shanghai Ruifu Chemical is the leading supplier of Darifenacin Hydrobromide (CAS: 133099-07-7) with high quality, commercial production. Darifenacin Hydrobromide is a selective M3 muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.
Ruifu Chemical has been supplying pharmaceutical intermediates and API (active pharmaceutical ingredient) more than 15 years, can provide worldwide delivery, competitive price, excellent service.
Purchase Darifenacin Hydrobromide other its intermediates, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name |
Darifenacin Hydrobromide |
| Synonyms |
Darifenacin HBr; UK-88525; Enablex |
| CAS Number |
133099-07-7 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C28H30N2O2.HBr |
| Molecular Weight |
507.46 |
| Melting Point |
228.0~230.0℃ |
| Solubility |
DMSO: Soluble 20mg/ml, Clear |
| Storage Temperature |
Store Long-term at 2-8℃ Refrigerator |
| Shipping Conditions |
Ambient |
| Shelf Life |
24 Months When Properly Stored |
| COA & MSDS |
Available |
| Place of Origin |
Shanghai, China |
| Product Categories |
API (Active Pharmaceutical Ingredient) |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White Crystalline Powder |
| Solubility |
Sparingly Soluble in Methanol, Slightly Soluble in Water and Practically Insoluble in Chloroform |
| Identification IR |
Spectrum of the sample corresponds to that of reference standard |
| Identification HPLC |
The retention time of the major peak of the sample solution corresponds to that of the standard solution |
| Related Substances |
|
| Max. Single Impurity |
≤0.50% |
| Total Impurities |
≤1.00% |
| Optical Isomer |
≤0.50% |
| Residual Solvents |
|
| Ethyl Acetate |
≤0.50% |
| Ethanol |
≤0.50% |
| Methanol |
≤0.30% |
| Acetone |
≤0.50% |
| 1-Butanol |
≤0.50% |
| Loss on Drying |
≤1.00% (Dry at 105℃ in an electric air blowing dryer till a constant weight) |
| Residue on Ignition |
≤0.10% |
| Heavy Metals |
≤20ppm |
| Assay / Analysis Method |
≥99.0% (HPLC) (on Dried Basis) |
| Shelf Life |
24 Months When Properly Stored |
| Test Standard |
Enterprise Standard |
Package: Bottle, aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Prevent direct sunlight; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
| WGK Germany |
3 |
| HS Code |
2934999099 |
Darifenacin Hydrobromide, Darifenacin HBr (CAS 133099-07-7), an orally active, once a day selective M3 receptor antagonist, was launched for the treatment of overactive bladder in patients with symptoms of urge urinary incontinence, urgency and frequency. The drug selectively inhibits M3 receptor in the detrusor muscle while sparing the M1 and M2 receptors that are believed to be involved in central nervous system and cardiovascular function respectively. The compound was originally developed by Pfizer and licensed to Novartis and Bayer.