Ruifu Chemical is the leading manufacturer of D-(-)-Fructose (CAS: 57-48-7) with high quality, can be used as a food additive and sweetener. Executive standards: GB/T 26762-2011 or USP 35. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase D-(-)-Fructose, Please contact: alvin@ruifuchem.com
| Chemical Name | D-(-)-Fructose |
| Synonyms | D-Fructose; Fructose; D-(-)-Levulose; D-Levulose; Fruit Sugar; D-Fructofuranose; beta-D-Fructopyranose; β-D-(-)-Fructose |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 57-48-7 |
| Molecular Formula | C6H12O6 |
| Molecular Weight | 180.16 g/mol |
| Melting Point | 119.0~122.0℃(dec.) (lit.) |
| Odor and Taste | Odorless, Sweet |
| Store Under Inert Gas | Store Under Inert Gas |
| Sensitive | Hygroscopic |
| Water Solubility | Soluble in Water |
| Solubility | Soluble in Alcohol. Insoluble in Ether |
| Stability | Stable. Incompatible with Strong Oxidizing Agents. |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Shelf Life | 24 Months If Stored Under Recommended Storage Conditions |
| Product Categories |
Food Additive and Sweetener; Sugars Carbohydrates |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White Crystals or Crystalline Powder | White Crystalline Powder |
| Solubility in Water | Colorless and Clear (50mg/ml) | Pass |
| Specific Rotation [a]20/D | -94.0° ~ -90.0° (C=10 in H2O) | Complies |
| Acidity | ≤0.50% | <0.50% |
| Loss on Drying | ≤0.50% | 0.09% |
| Residue on Ignition | ≤0.50% | 0.03% |
| Lead | ≤0.1mg/kg | 0.079mg/kg |
| Sulfate (SO42-) | ≤0.025% | <0.025% |
| Chloride (Cl) | ≤0.018% | <0.018% |
| Arsenic (As) | ≤0.0001% | Absent |
| Calcium and Magnesium | ≤0.005% | <0.005% |
| Heavy Metals (as Pb) | ≤0.0005% | <0.005% |
| Glucose | <0.50% | <0.50% |
| Hydroxymethylfurfural | ≤0.10% (on the Dry Basis) | 0.003% |
| Fructose Assay | 98.0%~102.0% (on the Dry Basis) | 99.5% |
| Total Plate Count | ≤100CFU/g | <10CFU/g |
| Yeast and Mould | ≤10CFU/g | <10CFU/g |
| Coliform | ≤30MPN/100g | <30MPN/100g |
| E. Coli | Not Detected | Absent |
| Salmonella | Not Detected | Absent |
| Staphyllococcus Aureus | Not Detected | Absent |
| Infrared Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Bottle; aluminium foil bag; packaged in multi-layer craft paper bag with food grade PE inner bags, net 25kg/bag. 25kg/cardboard drum with food grade PE inner bags. (Other packaging types are available on requests).
Storage Condition: Keep the container tightly closed, store in a cool, dry (2~8℃), well-ventilated warehouse. Keep away from direct sunshine; avoid fire and heat; avoid moisture. Incompatible with strong oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
Labeling: Each packing unit must carry a label indicating the name of the product, the net weight, the name of the manufacture, the date of production, the batch code, expiry date or shelf life and storage condition.
Fructose
C6H12O6 180.16
D-Fructose.
D-Fructose [57-48-7].
» Fructose, dried in vacuum at 70 for 4 hours, contains not less than 98.0 percent and not more than 102.0 percent of C6H12O6.
Packaging and storage- Preserve in well-closed containers.
USP Reference standards <11>-
USP Fructose RS
Identification, Infrared Absorption <197K>: previously dried.
Color of solution- Dissolve 25 g in water to make 50 mL: the solution has no more color than a solution prepared by mixing 1.0 mL of cobaltous chloride CS, 3.0 mL of ferric chloride CS, and 2.0 mL of cupric sulfate CS with water to make 10 mL, and diluting 3 mL of this solution with water to make 50 mL. Make the comparison by viewing the solutions downward in matched color-comparison tubes against a white surface.
Acidity- Dissolve 5.0 g in 50 mL of carbon dioxide-free water, add phenolphthalein TS, and titrate with 0.02 N sodium hydroxide VS to a distinct pink color: not more than 0.50 mL of 0.02 N sodium hydroxide is required for neutralization.
Loss on drying <731>- Dry it in vacuum at 70 for 4 hours: it loses not more than 0.5% of its weight.
Residue on ignition <281>: not more than 0.5%.
Chloride <221>- A 2.0-g portion shows no more chloride than corresponds to 0.50 mL of 0.020 N hydrochloric acid (0.018%).
Sulfate <221>- A 2.0-g portion shows no more sulfate than corresponds to 0.50 mL of 0.020 N sulfuric acid (0.025%).
Arsenic, Method II <211>- Prepare a Test Preparation by heating the acidified mixture nearly to dryness and cooling before 30% hydrogen peroxide is added. The limit is 1 ppm.
Calcium and magnesium (as calcium)- Dissolve about 20 g, accurately weighed, in 200 mL of water, and add 2 drops of hydrochloric acid, 5 mL of ammonia–ammonium chloride buffer TS, and 8 drops of eriochrome black TS. Mix, and titrate with 0.005 M edetate disodium VS to a blue endpoint. Each mL of 0.005 M edetate disodium is equivalent to 200.4 µg of Ca. Not more than 5.0 mL of 0.005 M edetate disodium is consumed (0.005% of Ca).
Heavy metals, Method I <231>- Dissolve 4 g in 23 mL of water, and add 2 mL of 1 N acetic acid: the limit is 5 ppm.
Limit of hydroxymethylfurfural- Transfer to a test tube 10 mL of a solution (1 in 10), add 5 mL of ether, and shake vigorously. Transfer 2 mL of the ether layer to a test tube, and add 1 mL of a 1 in 100 solution of resorcinol in hydrochloric acid: a slight pink color may develop, but no cherry-red color appears immediately.
Assay- Transfer about 10 g of Fructose, previously dried and accurately weighed, to a 100-mL volumetric flask, and dissolve in 50 mL of water. Add 0.2 mL of 6 N ammonium hydroxide, dilute with water to volume, and mix. After 30 minutes, determine the angular rotation in a 100-mm tube at 25 (see Optical Rotation <781>). The observed rotation, in degrees, multiplied by 1.124, represents the weight, in g, of C6H12O6 in the Fructose taken.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Codes C
Risk Statements 34
Safety Statements 24/25-45-36/37/39-27-26
WGK Germany 3
RTECS LS7120000
F 3
Autoignition Temperature 360℃
TSCA Yes
HS Code 1702500000
D-(-)-Fructose (CAS: 57-48-7) is a monosaccharide sugar found naturally in many fruits and vegetables, honey, and high fructose corn syrup. It is a monosaccharide, which means it cannot be broken down into simpler sugars. Fructose is a highly sweet substance, with a sweetness potency greater than that of glucose or sucrose. It is a key ingredient in many food and beverage products due to its sweet taste and solubility.
Fructose has potential applications in various fields of research and industry, including food and beverage, pharmaceuticals, personal care, cosmetics, and biotechnology. Fructose can be commercially used as a natural sweetener in food and beverage products, as a component in functional foods, and as an excipient in pharmaceutical preparations, syrups, and solutions. In biotechnology, Fructose is used as a carbon source for the production of biofuels and bioproducts.
Application of Crystalline Fructose:
Crystalline fructose has been used as a nutritive sweetener in foods and beverages. Also, it can be used as a humectant in cosmetics.
1, Food
Crystalline fructose is used as a flavor enhancer, flavoring agent or adjuvant, formulation aid, nutritive sweetener, processing aid, solvent or vehicle, stabilizer or thickener and texturizer in food.
2, Bakery
Crystalline fructose has good hygroscopicity and can be used in the processing of foods that need to be moisturized, such as bread and cakes.
It retains water in bakery products and so prolongs the shelf life.
In the bakery, it can also partially replace sucrose to accelerate Maillard reactions which are the chemical reactions between amino acids and reducing sugars. It produces an attractive brown color and aroma after baking.
3, Beverage
Crystalline fructose is a table sugar substitute as it improves and/or maintains flavor and has a low glycaemic index in beverage. The application such as in dry mix beverages, enhanced or flavored vitamin water, carbonated beverages, sports and energy drinks and etc.
It is used as a sugar substitute in foods and beverages including soft drinks, yogurt, industrial bread, cookies, salad dressing, and tomato soup. It is suitable for diabetics as its low glycemic response.
4, Medical applications: fructose used in medicine is crystalline fructose.
1) Fructose Injection.
2) Glycerol and Fructose Injection.Glycerin fructose injection is a new hypertonic injection, which is used in the treatment of cerebral hemorrhage and brain injury. It is a first-line drug to reduce intracranial pressure and eliminate cerebral edema. Glycerin fructose injection can effectively reduce intracranial pressure, eliminate brain edema, make patients awake early, reduce disability.
3) Fructose Vc tablet.
4) Pharmaceutical excipients.The glucose in medical syrup and tablet sugar can be converted to crystalline fructose, which is suitable for patients with diabetes and chronic liver disease.
5) Therapy products.
6) Pharmaceutical synthetic raw materials.Fructose is rapidly absorbed and metabolized, which can make up for alcohol-based hypoglycemia in time.
5, Others
Due to its sweetness, flavor enhancement and water retention properties, crystalline fructose can replace sorbitol and glycerol in foods, and it can improve the taste.
It can also be used in cereal bars, frozen foods, low-calorie products, chocolate milk, yogurt, ice-cream and confectionery.
6, Cosmetics
It functions as a humectant agent in cosmetic and personal care products.
Included in the FDA Inactive Ingredients Database (oral solutions, syrup, and suspensions; rectal preparations; intravenous infusions). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
