Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 2,2,2-Trifluoroethyl Trifluoromethanesulfonate (2,2,2-Trifluoroethyl Triflate) (CAS: 6226-25-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Welcome to place an order, Please contact: alvin@ruifuchem.com
| Chemical Name |
2,2,2-Trifluoroethyl Trifluoromethanesulfonate |
| Synonyms |
2,2,2-Trifluoroethyl Triflate; Trifluoromethanesulfonic Acid 2,2,2-Trifluoroethyl Ester; TFOL-TF |
| Stock Status |
In Stock, Commercial Production |
| CAS Number |
6226-25-1 |
| Molecular Formula |
C3H2F6O3S |
| Molecular Weight |
232.10 g/mol |
| Boiling Point |
89.0~91.0℃ |
| Flash Point |
>110℃(230°F) |
| Density |
1.61 g/cm3 |
| Refractive Index n20/D |
1.306 |
| Sensitive |
Moisture Sensitive |
| Water Solubility |
Slightly Soluble in Water |
| Storage Temp. |
Cool & Dry Place (2~8℃) |
| COA & MSDS |
Available |
| Origin |
Shanghai, China |
| Brand |
Ruifu Chemical |
| Items |
Inspection Standards |
Results |
| Appearance |
Colorless to Light Yellow Liquid |
Colorless Liquid |
| Purity / Analysis Method |
>98.0% (HPLC) |
98.66% |
| Trifluoromethanesulfonic Anhydride |
<1.00% |
0.48% |
| Sulfate Ion |
≤50 |
10 |
| Fluorinion |
≤50 |
5 |
| Refractive Index n20/D |
1.304~1.307 |
Complies |
| Density (20℃) |
1.608~1.619 |
Complies |
| Fluorine NMR Spectrum |
Conforms to Structure |
Complies |
| Infrared Spectrum |
Conforms to Structure |
Complies |
| 1 H NMR Spectrum |
Conforms to Structure |
Complies |
| Conclusion |
The product has been tested & complies with the given specifications |
Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Moisture sensitive. Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse. Protect from light and moisture. Incompatible with oxidizing agents and heat.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
R23/25 - Toxic by inhalation and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs 3265
WGK Germany 3
RTECS PB2775000
HS Code 2905 5900.90
Hazard Note Irritant
Hazard Class TOXIC, CORROSIVE
Packing Group Ⅱ
2,2,2-Trifluoroethyl Trifluoromethanesulfonate (2,2,2-Trifluoroethyl Triflate) (CAS: 6226-25-1), it can be prepared from trifluoroethanol by an acylation reaction with trifluoroacetic anhydride or trifluoromethanesulfonyl chloride.
Fluorination Reagents, Fluorinated Building Blocks, Sulfonylation Reagents. Intermediates in organic synthesis.
2,2,2-Trifluoroethyl Trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.
2,2,2-Trifluoroethyl Trifluoromethanesulfonate is used as a reagent in organic synthesis. It reacts with nucleophiles to form fluorinated products. The reaction can be observed by spectroscopic analysis and is useful for the synthesis of fluorinated molecules.