Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
| Chemical Name |
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine |
| Synonyms |
N-(5-Bromo-2-Chloropyrimidin-4-yl)(cyclopentyl)amine; 5-Bromo-2-Chloro-4-(Cyclopentylamino)pyrimidine |
| CAS Number |
733039-20-8 |
| CAT Number |
RF-PI1851 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C9H11BrClN3 |
| Molecular Weight |
276.56 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Off-White Powder |
| Purity / Analysis Method |
>99.0% (HPLC) |
| 1 H NMR Spectrum |
Consistent With Structure |
| Loss on Drying |
<1.00% |
| Total Impurities |
<1.00% |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Palbociclib (CAS: 571190-30-2)
|
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine (CAS: 733039-20-8) can be used as an intermediate of Palbociclib (CAS: 571190-30-2). Palbociclib (trade name: Ibrance) is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Palbociclib is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with: An aromatase inhibitor as initial endocrine based therapy in postmenopausal women; or Fulvestrant in women with disease progression following endocrine therapy.