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Commercial Supply Favipiravir (CAS: 259793-96-9) and Related Intermediates:
Favipiravir CAS: 259793-96-9
3,6-Dichloropyrazine-2-carbonitrile CAS: 356783-16-9
3,6-Difluoropyrazine-2-carbonitrile CAS: 356783-28-3
6-Bromo-3-hydroxypyrazine-2-carboxamide CAS: 259793-88-9
3-Hydroxypyrazine-2-Carboxamide CAS: 55321-99-8
2-Aminopropanediamide CAS: 62009-47-6
Diethyl Aminomalonate Hydrochloride CAS: 13433-00-6
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 3,6-Dichloropyrazine-2-carbonitrile (CAS: 356783-16-9) with high quality.
3,6-Dichloropyrazine-2-carbonitrile (CAS: 356783-16-9) is an intermediate typically in the synthesis of 6-Fluoro-3- hydroxypyrazine-2-carboxamide commercially named Favipiravir (CAS: 259793-96-9).
Favipiravir (CAS: 259793-96-9) in the treatment of Influenza virus infections. Favipiravir, also known as Favilavir, T705, or Avigan, is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated. The mechanism of its actions is thought to be related to the selective inhibition of viral RNA-dependent RNA polymerase. Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them. In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics.
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