Manufacturer with High Purity and Stable Quality
Chemical Name: 2-Butyl-4-chloro-5-formylimidazole (BCFI)
CAS: 83857-96-9
Intermediate of Antihypertensive drug Losartan Potassium (CAS 124750-99-8)
High Quality, Commercial Production
| Chemical Name |
2-Butyl-4-chloro-5-formylimidazole |
| Synonyms |
BCFI; 2-Butyl-5-chloro-1H-imidazole-4-carboxaldehyde |
| CAS Number |
83857-96-9 |
| CAT Number |
RF-PI319 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C8H11ClN2O |
| Molecular Weight |
186.64 |
| Density |
1.240 |
| Solubility |
Soluble in Methanol and Chloroform; Slightly Soluble in Water |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
Light Yellow to Yellow Crystalline Powder |
| Identification |
Must Conforms to the Reference Standard |
| Melting Point |
96.0~99.0℃(lit.) |
| Moisture Content (K.F) |
≤0.50% |
| Imidazolol |
Not Detected |
| Valeronitile |
≤0.15% |
| Single impurity |
≤0.15% |
| Total impurity |
≤1.0% |
| Purity / Analysis Method |
≥99.0% (by HPLC) |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Losartan Potassium (CAS 124750-99-8) Antihypertensive |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.
2-Butyl-4-chloro-5-formylimidazole (BCFI) (CAS 83857-96-9) is used for preparation of N-(biphenylylmethyl)imidazoles as angiotensin II antagonists. It's the Intermediate of Losartan Potassium (CAS 124750-99-8), a angiotensin II receptor antagonist. Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.