Manufacturer with High Purity and Stable Quality
Commercial Supply Pyrimidine Base Intermediates
| Cytosine CAS: 71-30-7 |
5-Azacytosine CAS: 931-86-2 |
| N4-Acetylcytosine CAS: 14631-20-0 |
N4-Benzoylcytosine CAS: 26661-13-2 |
| 5-Fluorocytosine CAS: 2022-85-7 |
|
| Uracil CAS: 66-22-8 |
5-Fluorouracil CAS: 51-21-8 |
| Chemical Name |
5-Fluorouracil |
| Synonyms |
5-FU |
| CAS Number |
51-21-8 |
| CAT Number |
RF-PI185 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C4H3FN2O2 |
| Molecular Weight |
130.08 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Almost White Crystalline Powder |
| Identification |
IR |
| Assay |
98.5%~101.0% |
| Loss on Drying |
≤0.50% |
| Residue on Ignition |
≤0.10% |
| Heavy Metals (Pb) |
≤20ppm |
| Chloride |
≤0.02% |
| Fluorine Content |
13.9%~15.0% |
| Test Standard |
Enterprise Standard; United States Pharmacopoeia (USP) |
| Usage |
Pharmaceutical Intermediates; Organic Synthesis |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Manufacturer with High Purity and Stable Quality
Commercial Supply Pyrimidine Base Intermediates
| Cytosine CAS: 71-30-7 |
5-Azacytosine CAS: 931-86-2 |
| N4-Acetylcytosine CAS: 14631-20-0 |
N4-Benzoylcytosine CAS: 26661-13-2 |
| 5-Fluorocytosine CAS: 2022-85-7 |
|
| Uracil CAS: 66-22-8 |
5-Fluorouracil CAS: 51-21-8 |
5-Fluorouracil (CAS: 51-21-8), RNA and DNA synthesis inhibitor, 5-Fluorouracil (CAS: 51-21-8) is an anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.
5-Fluorouracil (CAS: 51-21-8) is short for fluorouracil, and is pyrimidine antimetabolites, 5-fluorouracil as fluorouracil for pyrimidine antimetabolites, is currently clinically commonly used a chemotherapy drug, having effect on proliferation, can prevent the thymine formation, inhibition of DNA biosynthesis, thereby inhibiting the growth of cancer cells. Clinically, it is used to treat gastrointestinal tumors, such as stomach cancer, colon cancer, liver cancer and so on. In breast cancer, ovarian cancer, lung cancer, bladder cancer, cervical cancer, pancreatic cancer and so on are also effective. The Swiss production of skin cancer treatment ointment containing 5% of the goods, mainly used for actinic keratoses and senile keratosis, precancerous dermatitis, single and multiple shallow table basal cell carcinoma, radioactive skin lesion of carcinoma and superficial basal cell carcinoma.