Ruifu Chemical Supply Related Intermediates
CAS 361442-04-8
CAS 945667-22-1
(R)-1-Boc-3-Aminopiperidine CAS 188111-79-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7
| Chemical Name | 2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid |
| Synonyms | 3-Hydroxy- α-Oxoadamantane-1-Acetic Acid; 3-Hydroxy-Alpha-Oxoadamantane-1-Acetic Acid; 2-(3-Hydroxyadamantan-1-yl)-2-Oxoacetic Acid; 3-Hydroxy-α-Oxotricyclo[3.3.1.13,7]decane-1-Acetic Acid |
| CAS Number | 709031-28-7 |
| CAT Number | RF-PI2288 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.26 |
| Density | 1.477 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White to Off-White Crystal Powder (Visual) |
| Identification HPLC | The Retention Time of Major Peak Obtained from Sample Solution is Correspond to Reference Standard |
| Melting Point | 162.0~166.0℃ |
| Water (by Karl Fischer) | <0.50% (USP<921>) |
| Purity / Analysis Method | >99.0% (HPLC) |
| Assay | 98.0%~102.0% (On Dried Basis) |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of API (CAS: 361442-04-8) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid (CAS: 709031-28-7) is an intermediate of API (CAS: 361442-04-8), which is a type 2 diabetes drug that can stimulate the pancreas to produce more insulin after the meal. It was reached by the cooperation of AstraZeneca and Bristol-Myers Squibb Company and belongs to DPP-IV inhibitor. It plays the role through inhibiting GLP-l degradation. GLP-I is the hormones naturally produced in the intestine after taking food. It can regulate the secretion of insulin and strengthen the utilization of glucose in the peripheral tissues.