Ruifu Chemical is the leading manufacturer of 10-Deacetylbaccatin III (10-DAB; 10-DB III) (CAS: 32981-86-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 10-Deacetylbaccatin III, Please contact: alvin@ruifuchem.com
| Chemical Name |
10-Deacetylbaccatin III |
| Synonyms |
10-DAB; 10-DB III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(Benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-Tetrahydroxy-4a,8,13,13-Tetramethyl-7,11-methano-5H-Cyclodeca[3,4]benz[1,2-b]oxet-5-one; Docetaxel impurity E; |
| Impurity |
Paclitaxel - In House Impurity |
| Stock Status |
In Stock |
| CAS Number |
32981-86-5 |
| Molecular Formula |
C29H36O10 |
| Molecular Weight |
544.60 g/mol |
| Melting Point |
231.0~236.0℃ |
| Density |
1.41 g/cm3 |
| Sensitive |
Heat Sensitive |
| Water Solubility |
Insoluble in Water |
| Solubility |
Soluble in Methanol, DMSO |
| COA & MSDS |
Available |
| Origin |
Shanghai, China |
| Brand |
Ruifu Chemical |
| Items |
Inspection Standards |
Results |
| Appearance |
White to Off-White Crystalline Powder |
White Crystalline Powder |
| Identification (HPLC) |
Retention Time Similar to that of RS |
Complies |
| Specific Rotation [a]20/D |
-40.0° to -45.0° (C=1 in MeOH) |
-41.4° |
| Melting Point |
231.0~236.0℃ |
234.2℃ |
| Related Substances |
|
|
| Single Maximum Impurity |
<0.50% |
0.31% |
| Total Impurities |
<2.00% |
1.05% |
| Loss on Drying |
<0.50% |
0.32% |
| Residue on Ignition |
<0.20% |
0.02% |
| Heavy Metals (Pb) |
≤20ppm |
<20ppm |
| Assay |
98.0~102.0% |
100.3% |
| Infrared Spectrum |
Conforms to Structure |
Complies |
| Conclusion |
The product has been tested and complies with the given specifications |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols T - Toxic
Risk Codes 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S28A -
S24/25 - Avoid contact with skin and eyes.
UN IDs 1544
WGK Germany 3
HS Code 2932999025
Hazard Class 6.1(b)
Packing Group III
10-Deacetylbaccatin III (10-DAB; 10-DB III) (CAS: 32981-86-5) is an intermediate for the synthesis of taxol and its derivatives. 10-Deacetylbaccatin III is a precursor product for the synthesis of Paclitaxel and Docetaxel. 10-Deacetylbaccatin III is an impurity of Paclitaxel and derivatives. 10-Deacetylbaccatin-III is an anti-tumor agent and anti-cancer intermediate.
10-Deacetylbaccatin III is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented. By extracting the pre-cursor 10-DAB III in large quantites from the Taxus baccata leaf, many subsequent semiayntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and therefore the pharmacological profile of these important chemo-therapeutic agents.