Ruifu Chemical is the leading manufacturer of Trimethylsilylacetylene (Ethynyltrimethylsilane; TMS-Acetylene) (CAS: 1066-54-2) with high quality. Ruifu has been supplying Trimethylsilylacetylene more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Trimethylsilylacetylene or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | Trimethylsilylacetylene |
| Synonyms | TMSA; (Trimethylsilyl)acetylene; Ethynyltrimethylsilane; TMS-Acetylene |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 1066-54-2 |
| Molecular Formula | C5H10Si |
| Molecular Weight | 98.22 g/mol |
| Boiling Point | 53℃(lit.) |
| Flash Point | -34℃ |
| Specific Gravity (20/20) | 0.710 |
| Refractive Index n20/D | 1.390 |
| Store Under Inert Gas | Store Under Inert Gas |
| Sensitive | Air Sensitive, Moisture Sensitive |
| Water Solubility | Insoluble in Water |
| Solubility | Miscible with Organic Solvents |
| Storage Temperature | Store Long-Term at 2-8℃ |
| Hazard Class | 3; Flammable Liquid |
| COA & MSDS | Available |
| Sample | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
Silicon Compounds |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Colorless Liquid | Colorless Liquid |
| Assay / Analysis Method | ≥98.0% (GC) | 99.27% |
| Boiling Point | 53.0℃ | Complies |
| Density (20℃) | 0.710-0.713 | Complies |
| Refractive Index n20/D | 1.389-1.391 | Complies |
| Moisture | ≤0.50% | <0.10% |
| 1H NMR Spectrum | Consistent with Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Fluorinated bottle, 25kg/drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2-8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Incompatible with strong oxidizing agents.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes R11 - Highly Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
UN IDs UN 1993 3/PG 2
WGK Germany -
TSCA T
HS Code 2931900090
Hazard Note Flammable/Irritant
Hazard Class 3
Packing Group II
Precursor for Organic Synthesis:
Trimethylsilylacetylene (Ethynyltrimethylsilane; TMS-Acetylene) (CAS: 1066-54-2) serves as a versatile building block for organic synthesis due to the presence of the reactive ethynyl (C≡C) group. This group readily undergoes various reactions, allowing researchers to synthesize complex organic molecules with diverse functionalities.
Click Chemistry: Trimethylsilylacetylene participates in click chemistry reactions, a powerful tool for rapid and efficient formation of specific molecular bonds.
Sonogashira Coupling: This coupling reaction utilizes Trimethylsilylacetylene as a source of the ethynyl group, enabling the formation of carbon-carbon bonds between various organic fragments.
Modification of Biomolecules:
The ethynyl group in Trimethylsilylacetylene facilitates the selective modification of biomolecules, like proteins and nucleic acids. This modification allows researchers to:
Introduce Fluorescent Tags: Attaching fluorescent groups through the ethynyl moiety enables researchers to track and visualize the biomolecule within a cell.
Probe Biomolecular Interactions: By incorporating Trimethylsilylacetylene-derived tags, scientists can investigate interactions between biomolecules, providing insights into cellular processes.
Material Science Applications:
The unique properties of Trimethylsilylacetylene make it valuable in material science research for the development of:
Polymers: Incorporation of Trimethylsilylacetylene units into polymer chains can enhance their thermal stability, mechanical properties, and conductivity.
Organic Electronics: Trimethylsilylacetylene serves as a precursor for the synthesis of organic light-emitting diodes (OLEDs) and organic solar cells due to its ability to form conjugated structures.