Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of p-Toluenesulfonylmethyl Isocyanide (TosMIC; Tosylmethyl Isocyanide) (CAS: 36635-61-7) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase TosMIC, Please contact: alvin@ruifuchem.com
| Chemical Name | p-Toluenesulfonylmethyl Isocyanide |
| Synonyms | TosMIC; Tosylmethyl Isocyanide; (p-Tolylsulfonyl)methyl Isocyanide; 1-[(Isocyanomethyl)sulfonyl]-4-Methylbenzene; p-Toluenesulfonylmethyl Isocyanide; p-Toluenesulfonylmethylisonitrile; p-Tosylmethyl Isocyanide; p-Tosylmethyl Isonitrile |
| Stock Status | In Stock, Commercially Manufactured |
| CAS Number | 36635-61-7 |
| Molecular Formula | C9H9NO2S |
| Molecular Weight | 195.24 g/mol |
| Melting Point | 108.0~115.0℃ |
| Sensitive | Moisture, Heat, Air and Light Sensitive |
| Solubility | Soluble in Chloroform and Methanol. Insoluble in Water |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Light Yellow to Light Brown Crystalline Powder | Complies |
| Melting Point | 108.0~115.0℃ | 110.0~112.0℃ |
| Loss on Drying | <0.50% | 0.15% |
| Residue on Ignition | <0.20% | 0.08% |
| Heavy Metals (Pb) | ≤20ppm | <20ppm |
| Purity / Analysis Method | >99.0% (HPLC) | 99.5% |
| Purity (Titration) | 97.5~102.5% | Complies |
| Infrared Spectrum | Conforms to Structure | Complies |
| NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Moisture, heat, air and light sensitive. Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with strong bases and strong oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S28A -
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
FLUKA BRAND F CODES 21
HS Code 2935900090
Hazard Note Irritant
Hazard Class 6.1(b)
Packing Group III
p-Toluenesulfonylmethyl Isocyanide (TosMIC; Tosylmethyl Isocyanide) (CAS: 36635-61-7) is used as an organic synthesis intermediate, pharmaceutical intermediate, pesticide intermediate, or chemical reagent.
Tosylmethyl Isocyanide is used as a synthetic reagent in the preparation of variety or biologically active heterocycles such as pyrroles and imidazoles. As isonitrile components, used in stereoselective Passerini reactions containing carbohydrate-derived aldehydes.
Versatile synthon in organic chemistry, especially in the synthesis of heterocyclic compounds.
Tosylmethyl Isocyanide contains both sulfonyl and isocyanide groups. Unlike many isocyanides, it is odorless. It is prepared by dehydration of the related formamide derivative. It is used in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles.