Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Sulfanilamide (CAS: 63-74-1) with high quality, commercial production. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Sulfanilamide, Please contact: alvin@ruifuchem.com
| Chemical Name | Sulfanilamide |
| Synonyms | C-SN; 4-Aminobenzenesulfonamide; p-Aminobenzenesulfonamide |
| Stock Status | In Stock, Production Capacity 2000 Tons |
| CAS Number | 63-74-1 |
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.20 g/mol |
| Melting Point | 164.5~166.5℃ |
| Density | 1.08 |
| Water Solubility | Practically Insoluble in Water, 7.5 g/l 25℃ |
| Solubility | Soluble in Ethanol, Acetone. Insoluble in Ether, Benzene, Chloroform |
| COA & MSDS | Available |
| Sample | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White Crystalline Granular or Powder | Complies |
| Melting Point | 164.5~166.5℃ | 165.3~165.7℃ |
| Purity / Analysis Method | >99.5% (HPLC) | 99.8% |
| Loss on Drying | ≤0.50% | 0.06% |
| Residue on Ignition | ≤0.10% | 0.06% |
| Acidity | ≤0.1mol/L NaoH 0.2ml | Conforms |
| Clarity of Solution | Clarity | Clarity |
| Related Substances | <0.50% | <0.50% |
| Heavy Metals (as Pb) | ≤10ppm | <10ppm |
| Iron (Fe) | ≤5ppm | <5ppm |
| Chloride (Cl-) | ≤100ppm | <100ppm |
| Sulfate (SO42-) | ≤200ppm | <200ppm |
| 1 H NMR Spectrum | Consistent with Structure | Complies |
| LCMS | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Avoid exposure to direct sunlight, moisture and excessive heat.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xn - Harmful
Risk Codes 40 - Limited evidence of a carcinogenic effect
Safety Description S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S22 - Do not breathe dust.
WGK Germany 3
RTECS WO8400000
FLUKA BRAND F CODES 10
TSCA Yes
HS Code 2935900090
Hazard Class 8
Toxicity LD50 orally in mice: 3.8 g/kg (Marshall)
Sulfanilamide (CAS: 63-74-1) is an organic sulfur compound structurally similar to p-aminobenzoic acid (PABA) with antibacterial property. Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.Without it, bacteria cannot replicate.
Mechanism of action: mechanism of action is to interfere with the synthesis of nucleic acids required for pathogenic microorganisms,making bacteria lack of nutrition and stop the growth, development and reproduction, having suppression killing effect on hemolytic streptococcus, staphylococcus and meningococcal.
Pharmacodynamics: Oral easily absorbed from the gastrointestinal tract, widely distributed in the body, can penetrate the blood-brain barrier into the brain tissue, and can penetrate the placental barrier into the fetus. Rapid excretion, mainly excreted in metabolites from kidney.
Clinical application: Mainly used for trauma infection caused by infection hemolytic streptococcus, staphylococcus, and local wound infections.
Uses: Sulfanilamide is lower toxicity in sulfa drugs, can be applied for infants, pregnant women, pregnant women and during menstruation, but not in large doses. Having effects on hemolytic streptococcal infection (erysipelas, puerperal fever, tonsillitis), urinary tract infection (gonorrhea) and so; also the intermediate for synthesis of other sulfa drug (such as sulfa amidine, pyrimidine and sulfamethoxazole sulfa methoxy-triazine, etc.).
1. Sulfanilamide is used in the pharmaceutical industry, is the main raw material of the synthesis of sulfonamides.
2. Used as a reagent to determine nitrite, also used in the pharmaceutical industry.
3. Used as intermediates for the synthesis of other sulfa drugs, even for wound disinfection.
4. Amino benzene sulfonamide is intermediate of herbicide asulam, as well as intermediate of sulfa medicine.
5. Veterinary medicine, topical anti-inflammatory drugs, for analysis and detection.
6. Wide spectrum antibacterial, having antibacterial effects on hemolytic streptococcus, Neisseria meningitidis, Staphylococcus aureus and other Gram-positive and negative bacteria. This product is topical application, it can be partially absorbed from the wound. For trauma infections of hemolytic streptococcus and staphylococcus. It can also be used to quickly stop the bleeding wound.