Manufacturer Supply with High Purity and Stable Quality
Chemical Name: Sevelamer Carbonate CAS: 845273-93-0
Appearance: White to Yellowish Powder
Binding of Phosphate: 3.0~7.0mmol/g
Sevelamer Carbonate is a polymeric amine that binds phosphate and is used to treat hyperphosphatemia in patients with chronic kidney disease
API High Quality, Commercial Production
| Chemical Name |
Sevelamer Carbonate |
| Synonyms |
2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate |
| CAS Number |
845273-93-0 |
| CAT Number |
RF-API28 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
(C3H7N)m.(C3H5ClO)n.(CH2O3)x |
| Molecular Weight |
211.64 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Yellowish Powder |
| Identification A |
By IR, To match with working standard |
| Identification B |
Should be positive reaction |
| Chloride |
≤0.10% |
| Loss on Drying |
≤10.0% |
| Residue on Ignition |
≤0.20% |
| Heavy Metals |
≤20ppm |
| Solubility Test |
Should be to match with the standard |
| Binding of Phosphate |
3.0~7.0mmol/g |
| Soluble Oligomer |
≤0.20% |
| Test Standard |
Enterprise Standard |
| Attention |
Protect from the light and Store in a cool dry place(≤5℃), Best use within six months |
| Usage |
Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Sevelamer carbonate is a polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease. Sevelamer carbonate is an anion exchange resin, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. While the counterions differ for the two salts, the polymer itself, the active moiety involved in phosphate binding, is the same. Sevelamer carbonate is known chemically as poly(allylamine-co-N,N'-diallyl-1,3diamino-2-hydroxypropane) carbonate salt. Sevelamer carbonate is hygroscopic, but insoluble in water. Sevelamer Carbonate, a non-absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-based phosphate binders.