Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Prostaglandin E1 (Alprostadil; PGE1) (CAS: 745-65-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Prostaglandin E1, Please contact: alvin@ruifuchem.com
| Chemical Name | Prostaglandin E1 |
| Synonyms | Alprostadil; PGE1; (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid; (11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic Acid; ent-PGE1 |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 745-65-3 |
| Molecular Formula | C20H34O5 |
| Molecular Weight | 354.49 |
| Melting Point | 115.0 to 119.0℃ |
| Density | 1.13 |
| Sensitive | Heat Sensitive |
| Water Solubility | Insoluble in Water |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White or Slightly Yellowish Crystalline Powder | Conforms |
| Identification (1) HPLC The retention time of the major peak in the chromatogram of Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay Conforms | ||
| Identification (2) IR Absorbance Spectrum Both the test sample and the reference standard exhibit the same intensity of absorption at the same wave number(wavelengths). (potassium bromide disk method) Conforms | ||
| Optical Rotation | -60.0° to -70.0° (Anhydrous Substance) | -69.4° |
| Water by Karl Fischer | <0.50% | 0.19% |
| Residue on Ignition | <0.50% | 0.21% |
| Related Substances | ||
| Impurity A | <1.50% | Not Detected |
| Impurity B | <0.50% | Not Detected |
| Any Other Impurity | <0.90% | 0.26% |
| N.M.T One Impurity | <0.50% | Not Detected |
| Total Impurities | <1.50% | 0.51% |
| Residual Solvents | ||
| Ethyl Acetate | <0.50% | 0.0484% |
| n-Heptane | <0.50% | 0.0056% |
| Acetone | <0.50% | Not Detected |
| n-Hexan | <0.029% | Not Detected |
| Assay | 95.0~102.5% (Anhydrous and Solvent Free Basis) | 99.8% |
| Conclusion | Conforms to the Requirements of EP7.0 | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (-20℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R61 - May cause harm to the unborn child
Safety Description S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
RTECS GY4569800
FLUKA BRAND F CODES 8-10
HS Code 2937500090
Hazard Class 6.1(b)
Packing Group III
Prostaglandin E1 (Alprostadil; PGE1) (CAS: 745-65-3) is a biologically active substance widely present in the body. It is a member of the prostaglandin family and is recognized as an endogenous physiologically active substance. Prostaglandin E1 acts directly on vascular smooth muscle, dilates blood vessels, increases blood flow, improves microcirculation perfusion, inhibits platelet aggregation and thromboxane A2 production, and inhibits atherosclerosis, lipid plaque and immune complex formation; dilate peripheral small vessels and coronary arteries, reduce peripheral vascular resistance and blood pressure, protect platelet membrane, prevent thrombosis; Protect ischemic myocardium, reduce myocardial infarction area; Anti-heart failure; Dilate renal vessels, increases renal blood flow, removes non-protein nitrogen, regulates water-sodium balance, has a diuretic and protective effect on renal function.
Used for diabetic neuropathy, myocardial infarction, thrombotic vasculitis, arteriosclerosis obliterans, central retinal vein thrombosis. It is used in the treatment of hepatitis cirrhosis, cerebral infarction, diabetes, impotence, respiratory diseases. Liver damage is not serious childA, class B patients, especially patients with antithrombin level childA China effect. For induction of labor, oxytocin, renal insufficiency, treatment mumps, pancreatitis. Injection of Prostaglandin E1 is mainly applied to myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusive disease, central retinal vein thrombosis, platelet protection for extracorporeal circulation, arteriography, revascularization surgery.