Factory Supply Posaconazole Related Intermediates, Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
| Chemical Name |
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde |
| Synonyms |
N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide; N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide; Posaconazole Intermediate; Posaconazole Impurity 33 |
| CAS Number |
170985-85-0 |
| CAT Number |
RF-PI292 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C13H20N2O2 |
| Molecular Weight |
236.31 |
| Shipping Condition |
Shipped Under Ambient Temperature |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Off-White Powder |
| Identification |
H-NMR: Conforms to the Standard |
| Loss on Drying |
≤0.50% |
| Purity / Analysis Method |
≥98.0% (HPLC) |
| Organic Impurities |
|
| Any Single Impurity |
≤0.50% |
| Total Organic Impurities |
≤2.0% |
| Heavy Metals |
≤20ppm |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Posaconazole (CAS 171228-49-2) Antifungal Agent |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
2-[(1S,2S)-1-Ethyl-2-(Phenylmethoxy)propyl]hydrazinecarboxaldehyde (CAS: 170985-85-0) is an important intermediate of Posaconazole (CAS 171228-49-2). Posaconazole is a triazole antifungal drug widely used in the treatment of invasive infections. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Posaconazole is derived from itraconazole. Its pharmacological effects are similar with azoles, but compared with Itraconazole, it has a stronger inhibitory effect on the C14 demethylation of steroid, especially for Aspergillus. Posaconazole, launched in the UK, is the newest member of the azole class of antifungal agents to reach the market.