Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Pimasertib (AS-703026) (CAS: 1236699-92-5) with high quality. Ruifu Chemical has been supplying pharmaceutical intermediates and APIs more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Pimasertib (AS-703026) or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | Pimasertib |
| Synonyms | AS-703026; AS 703026; MSC1936369B; N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide; N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide; (S)-N-(2,3-Dihydroxypropyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide |
| Stock Status | In Stock |
| CAS Number | 1236699-92-5 |
| Molecular Formula | C15H15FIN3O3 |
| Molecular Weight | 431.2 g/mol |
| Melting Point | 164.0~169.0℃ |
| Density | 1.769 |
| Refractive Index n20/D | 1.684 |
| Solubility | DMSO 86 mg/mL |
| Storage Temperature | Store Long-Term at -20℃ |
| Shipping Conditions | Shipped Under Ambient Temperature for Short Term |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Application(s) |
MEK1/2 Inhibitor |
| Caution | Not For Human or Veterinary Use. For Research Use Only. |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Yellow Solid | Yellow Solid |
| Pimasertib Purity | >99.0% (HPLC) | 99.7% |
| 1H NMR Spectrum | Consistent with Structure | Conforms |
| LC-MS | Consistent with Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Bottle, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store long-term at -20℃. Keep away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Pimasertib (AS-703026) (CAS: 1236699-92-5) is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation.
Pimasertib is a novel, small-molecule, dual inhibitor of MEK and PI3K/mTOR. It is a promising drug candidate for the treatment of a variety of cancers, including colon, breast, ovarian, and pancreatic cancer. Pimasertib has a unique mechanism of action, which is thought to be synergistic with other cancer treatments.