Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Phenacetin (CAS: 62-44-2) with high quality. Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Phenacetin or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | Phenacetin |
| Synonyms | N-Acetyl-4-Ethoxyaniline; N-Acetyl-p-Phenetidine; 1-Acetyl-p-Phenetidin; 4'-Ethoxyacetanilide; 4-Acetophenetidide; N-(4-Ethoxyphenyl)acetamide; p-Acetophenetidide; Acetophenetidin |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 62-44-2 |
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.22 g/mol |
| Melting Point | 134.0 to 138.0℃ |
| Boiling Point | 132℃/4 mmHg |
| Refractive Index n20/D | 1.51 |
| Sensitive | Hygroscopic |
| Water Solubility | Insoluble in Water |
| Solubility | Soluble in Chloroform, Acetone. Slightly Soluble in Ether, Benzene |
| Storage Temperature | Store Long-Term at 2-8℃ |
| Stability | Stable. Incompatible with Strong Oxidizing Agents, Strong Acids. |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
API (Active Pharmaceutical Ingredient) |
| Caution | Not For Human or Veterinary Use. For Research Use Only. |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White Glistening Crystalline Scales or a Fine White Crystalline Powder |
Conforms |
| Odor & Taste | Odorless, Taste Slightly Bitter | Conforms |
| Identification | A. Positive | Conforms |
| Identification | B. Positive | Conforms |
| Melting Point | 134.0-138.0℃ | 134.0-136.0℃ |
| 4-Chloroacetanilide | Should Meet the Requirement | Conforms |
| P-Phenetidine | Should Meet the Requirement | Conforms |
| Sulphated Ash | ≤0.10% | 0.04% |
| Assay / Analysis Method | ≥99.0% (HPLC) (On Dry Basis) | 99.6% |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes R45 - May cause cancer
R22 - Harmful if swallowed
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36 - Irritating to the eyes
R11 - Highly Flammable
Safety Description S53 - Avoid exposure - obtain special instructions before use.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37 - Wear suitable protective clothing and gloves.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16 - Keep away from sources of ignition.
UN IDs UN 3077 9 / PGIII
WGK Germany 3
RTECS AM4375000
TSCA Yes
HS Code 2924291000
Phenacetin (CAS: 62-44-2) was used as an analgesic and antipyretic drug in both human and veterinary medicine for many years. It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease (nephropathy) due to abuse of analgesics (Flower et al. 1985) and was withdrawn from the U.S. market in 1983 (Ronco and Flahault 1994, FDA 1998, 1999).
The drug was initially used to treat mild to moderate pain, fever, and inflammation. Phenacetin has since been withdrawn from the market due to its potential to cause kidney and liver damage, as well as its potential to cause cancer. Despite its dangers, phenacetin is still used in some countries as an analgesic and antipyretic.
Phenacetin (CAS: 62-44-2) is mainly used as an antipyretic analgesic, with slow and lasting effects, treating headaches, neuralgia, joint pain, and fever, and weakly resisting rheumatism and inflammation. Because of toxic side effects and the rapid development of similar drugs, however, it is no longer used alone, only as a raw material in combination with other drugs. Commonly combined with aspirin and caffeine to form a less toxic compound aspirin used to treat the common cold. Can make chlorpheniramine cold tablets by adding a small amount of chlorpheniramine to the above compound, used to treat colds with headache, neuralgia, rheumatism, etc. Can be used as a material for organic synthesis or a pharmaceutical intermediate.
Phenacetin (CAS: 62-44-2) acts as an analgesic and antipyretic by inhibiting the synthesis of prostaglandins. Prostaglandins are inflammatory mediators that are involved in the sensation of pain and fever. By blocking the synthesis of prostaglandins, phenacetin reduces pain and fever.
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.