Manufacturer Supply Perindopril Erbumine Related Intermediates
L-Octahydroindole-2-Carboxylic Acid CAS 80875-98-5
(S)-(-)-Indoline-2-Carboxylic Acid CAS 79815-20-6
(±)-Indoline-2-Carboxylic Acid CAS 78348-24-0
N-[(S)-Ethoxycarbonyl-1-Butyl]-(S)-Alanine CAS 82834-12-6
Perindopril Erbumine CAS 107133-36-8
| Chemical Name | Perindopril Erbumine |
| Synonyms | Perindopril tert-Butylamine Salt; Aceon; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt |
| CAS Number | 107133-36-8 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C19H32N2O5.C4H11N |
| Molecular Weight | 441.61 |
| Melting Point | 126.0~128.0℃ |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Off-White Crystalline Powder |
| Identification | IR; HPLC |
| Specific Rotation [α]D20 | -66.0°~-69.0° |
| Impurities A | ≤0.25% |
| Impurities I | ≤0.10% |
| Unknown Impurities | ≤0.10% |
| Impurities E | ≤0.40% |
| Impurities B | ≤0.30% |
| Impurities F | ≤0.20% |
| Impurities H | ≤0.20% |
| Unknown Impurities | ≤0.10% |
| Total Impurities | <0.50% |
| Water Content | ≤1.00% |
| Residue on Ignition | ≤0.10% |
| Heavy Metals | ≤20ppm |
| Purity / Analysis Method | >99.5% (HPLC) |
| Related Substances | Meet the Specification |
| Test Standard | Enterprise Standard |
| Usage | API; ACE Inhibitor; Antihypertensive |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Perindopril Erbumine (CAS: 107133-36-8), also known as Perindopril tert-Butylamine Salt, is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. Inhibition of this enzyme prevents the formation of angiotensin II from angiotensin I, which in turn prevents vasoconstriction caused by angiotensin II. Perindopril Erbumine is an orally bioavailable long acting angiotensin converting enzyme (ACE) inhibitor (IC50 value of 10 μM). Specifically, Perindopril Erbumine is an oral prodrug of Perindoprilat, a potent ACE inhibitor with an IC50 value of 1.9 nM.