Manufacturer Supply with High Purity and Stable Quality, Commercial Production
| DL-Pipecolinic Acid | 2-Piperidinecarboxylic Acid | CAS 535-75-1 |
| Nipecotic Acid | 3-Piperidinecarboxylic Acid | CAS 498-95-3 |
| Isonipecotic Acid | 4-Piperidinecarboxylic Acid | CAS 498-94-2 |
| Chemical Name | Nipecotic Acid |
| Synonyms | DL-Nipecotic Acid; 3-Piperidinecarboxylic Acid; H-DL-Nip-OH |
| CAS Number | 498-95-3 |
| CAT Number | RF-PI284 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C6H11NO2 |
| Molecular Weight | 129.16 |
| Water Solubility | Soluble in Water |
| Shipping Condition | Shipped Under Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Yellowish Crystalline Powder |
| Decompose Temperature | ≥261.0℃ |
| Identification | IR, NMR |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤1.0% |
| Assay / Analysis Method | ≥98.0% (TLC) |
| Test Standard | Enterprise Standard; Chinese Pharmacopoeia (CP) |
| Usage | Pharmaceutical Intermediates |
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Nipecotic Acid (CAS: 498-95-3) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and Active Pharmaceutical Ingredient (API) synthesis. Nipecotic Acid (CAS: 498-95-3) is a potential inhibitor of uptake of γ-aminobutyric acid (GABA) in rat brain slices. Lipophilic derivatives of nipecotic acid are used as drugs for the treatment of epilepsy.
Application
Nipecotic acid was used in determination of the antiepileptic drug vigabatrin and the amino acid neurotransmitters in rat brain extracellular fluid by capillary; electrophoresis with laser-induced fluorescence detection; Reactant for concurrent esterification and N-acteylation of amino acids with orthoesters
Reactant for synthesis of:
Anticonvulsants: HCV NS5B polymerase inhibitors; Cathepsin S inhibitors; Orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation; Positive allosteric modulator of metabotropic glutamate receptor 4