Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Acetylneuraminic Acid (Synthetic) (CAS: 131-48-6) with high quality. It is used in the pharmaceuticals, health care, nutritional supplements, food additives, cosmetic ingredients, and other fields. Ruifu Chemical can provide competitive price, excellent service.
Purchase N-Acetylneuraminic Acid or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | N-Acetylneuraminic Acid |
| Synonyms | N-(-)-Acetylneuraminic Acid; NANA; 5-Acetamido-3,5-Dideoxy-D-Glycero-D-Galacto-Nonulopyranosonic Acid; NAN; Neu5Ac; Sialic Acid; o-Sialic Acid; Lactaminic Acid; 5-N-Acetyl-beta-D-Neuraminic Acid |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 131-48-6 |
| Molecular Formula | C11H19NO9 |
| Molecular Weight | 309.27 g/mol |
| Melting Point | 184.0~186.0℃ |
| Specific Rotation [a]20/D | -30.0° to -34.0° (C=1, H2O) |
| Store Under Inert Gas | Store Under Inert Gas |
| Sensitive | Air Sensitive, Heat Sensitive |
| Water Solubility | Soluble in Water (50 mg/ml) |
| Storage Temperature | Store Long-Term at <0℃ |
| Stability | Stable. Incompatible with Strong Oxidizing Agents |
| Shelf Life | 24 Months If Stored Properly and In Original Package |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results | Method of Analysis |
| Appearance | White Powder | White Powder | Visual |
| Impurities | No Visible Impurities | Conforms | Visual |
| Smell & Taste | Sweet and Sour Taste | Conforms | Organoleptic |
| Assay / Analysis Method | ≥98.0% (HPLC) | 98.40% | HPLC |
| pH | 1.8~2.3 | 2.15 | GB 5009.237 |
| Loss on Drying | ≤2.00% (105℃, 3 h) | 1.66% | GB 5009.3 |
| Optical Rotation | -30.0°~-34.0° | -32.1° | GBT 613-2007 |
| Ignition Residue | ≤2.00% | 0.08% | GB 5009.4 |
| Aflatoxin B1 | ≤0.5μg/kg | Not Detected | GB 5009.22 |
| Pb | ≤1.0ppm | Not Detected | GB 5009.12 |
| As | ≤1.0ppm | Not Detected | GB 5009.11 |
| Hg | ≤0.2ppm | Not Detected | GB 5009.17 |
| Microbiological Test | |||
| Total Plate Count | ≤1000cfu/g | 70cfu/g | GB 4789.2 |
| Yeasts and Moulds | ≤100cfu/g | Not Detected | GB 4789.15 |
| Enterobacteriaceae | ≤60MPN/100g | Not Detected | GB 4789.2 |
| Staphylococcus Aureus | Not Detected | Not Detected | GB 4789.10 |
| Salmonella | Not Detected | Not Detected | GB 4789.4 |
| Conclusion | The product has been tested and complies with the given specifications | ||
Package: Bottle, Aluminium foil bag, 25kg/cardboard drum (inner by double plastic bags ), or according to customer's requirement.
Storage Condition: Air sensitive. Store under inert gas. Store away from oxidizing agents, air. Keep the container tightly closed and store in a cool, dry (<0℃) and well-ventilated warehouse. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
FLUKA BRAND F CODES 3-10-23
TSCA Yes
HS Code 2932999099
Hazard Note Irritant
N-Acetylneuraminic Acid (NANA; Sialic Acid) (CAS: 131-48-6) is an N-acyl derivative of neuraminic or acid amino sugar derivative, derived from N-acetylmannosamine and pyruvic acid. It is an important constituent of glycoproteins and glycolipids. N-Acetylneuraminic Acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
N-Acetylneuraminic Acid is a key component of important amino sugars that mediate cellular communication. It is a naturally-occuring building block foe compounds such as glycoproteins and gangliosides.
N-Acetylneuraminic Acid (NANA; Sialic Acid) (CAS: 131-48-6) is an integral part of sialic acids (SAs), important functional sugars that play an important role in maintaining and improving brain health, detoxification, antibacterial, and immune enhancement. N-Acetylneuraminic Acid is biologically useful for neurotransmission, leukocyte extravasation, viral or bacterial infection, and carbohydrate-protein recognition. N-Acetylneuraminic Acid is used to study its biochemistry, metabolism and absorption in vivo and in vitro.
1. Anti-virus function.
2. Anti-cancer function.
3. Anti-inflammation function.
4. Defensive function against bacteriological infectiong.
5. Controlling ability of immune system.
6. Restraining ability against pigmentation.
7. Signal transformation in nerve cells.
8. Play a key role in brain development and learning.
9. As precursor for the manufacture of many pharmaceutical drugs.
In food and supplement field
-N-Acetylneuraminic Acid is the predominant component found in the brain, it is proved to be the key material in memory and learning function.
-N-Acetylneuraminic Acid is one of the nutritional component of human milk, it improves brain development of infants. Applied in Infant food. Adding infant milk powder can increase babys' intelligence and memory
-As one of the eight essential glyconutrients for huamn body, it widely exists in the cell membrane and neuron. It can enhance the body immunity. Appled in Health food.
In cosmetic field
-Anti-aging: N-Acetylneuraminic Acid is a natural MMP-1 inhibitor. By reducing the expression of MMP-1 and its activity. N-Acetylneuraminic Acid could enable the aged disease cells back to normal status, and maintain the cell stability, greatly reduce the speed of cekk recession. And prolong the lifespan of skin cells so as ti achieve the effect of anti-aging. Therefore, long-term using skincare products containong N-Acetylneuraminic Acid could effectively delay skin aging and promote skin regeneration. Applied in cosmetic products to removing wrinkles.
-Whitening: N-Acetylneuraminic Acid can effectively inhibit tyrosine hydroxylase and dopa hudroxylase activity, preventing melanin basically.
In pharmaceuticals field
-Starting reagent of biochemical derivatives for the synthesis pharmaceuticals. Apllied in prodrugs.