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Commercial Supply Indinavir Sulfate (CAS: 157810-81-6) Related Intermediates:
(1R,2S)-(+)-1-Amino-2-indanol CAS: 136030-00-7
(1S,2R)-(-)-1-Amino-2-indanol CAS: 126456-43-7
| Chemical Name |
(1S,2R)-(-)-1-Amino-2-indanol |
| Synonyms |
(1S,2R)-(-)-1-Amino-2-hydroxyindan |
| CAS Number |
126456-43-7 |
| CAT Number |
RF-CC120 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C9H11NO |
| Molecular Weight |
149.19 |
| Solubility (Soluble in) |
Methanol |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Pale Yellow Powder |
| Specific Rotation [α]D20 |
-47.0°~ -42.0° (C=1,MeOH) |
| Melting Point |
115.0～121.0℃ |
| Purity / Analysis Method |
≥99.0% (HPLC) |
| Loss on Drying |
≤0.50% |
| Moisture (K.F) |
≤0.50% |
| E.E |
≥99.0% |
| Test Standard |
Enterprise Standard |
| Usage |
Indinavir Sulfate (CAS: 157810-81-6) Intermediates |
Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) with high quality. (1S,2R)-(-)-1-Amino-2-indanol (CAS: 126456-43-7) is an intermediate typically in the synthesis of Indinavir Sulfate (CAS: 157810-81-6).
Indinavir Sulfate (CAS: 157810-81-6) (MK-639) is a protease inhibitor used as a component of highly active antiretroviral therapy (HAART) to treat HIV infection and AIDS. MK-639 appears to have significant dose-related antiviral activity and is well tolerated. Indinavir is a potent inhibitor of HIV reverse transcriptase. It produces the side effects common to all protease inhibitors and also may produce nephrolithiasis, urolithiasis, and possibly renal insufficiency or renal failure. This problem occurs more frequently in children (approximately 30%) than adults (approximately 10%) and can be minimized by drinking at least 1.5 L of water daily. Additional side effects include asymptomatic hyperbilirubinemia, alopecia, ingrown toenails, and paronychia. Hemolytic anemia rarely occurs. Rifampin should not be given with indinavir.