Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of L-Norleucine (H-Nle-OH) (CAS: 327-57-1) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase L-Norleucine, Please contact: alvin@ruifuchem.com
| Chemical Name | L-Norleucine |
| Synonyms | L-(+)-Norleucine; H-Nle-OH; L-Nle-OH; Laevo-Norleucine; (S)-Norleucine; L-2-Aminohexanoic Acid; (S)-2-Aminohexanoic Acid; (S)-(+)-2-Aminohexanoic Acid; (S)-2-Aminocaproic Acid; L-2-Aminohexanoic Acid; α-Aminocaproic Acid |
| Stock Status | In Stock, Production Capacity To Tons |
| CAS Number | 327-57-1 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.18 g/mol |
| Melting Point | >300℃(lit.) |
| Density | 1.038 |
| Solubility in Water | Soluble |
| Solubility in Hot Water | Almost Transparency |
| Storage Temp. | Cool & Dry Place (≤25℃) |
| COA & MSDS | Available |
| Category | Unusual Amino Acids |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White or Off-White Crystalline Powder | Complies |
| Specific Rotation [α]20/D | +22.0° to +24.0° (C=5 in 5N HCl) |
+23.1° |
| Loss on Drying | <0.30% | 0.10% |
| Residue on Ignition | <0.20% | 0.09% |
| Other Amino Acid | <0.10% | 0.09% |
| D-Isomer Content | <0.50% | 0.35% |
| Chloride (Cl) | <0.10% | Complies |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| IR Spectrum | Consistent With Structure | Complies |
| L-Norleucine Assay | 99.0~101.0% | 99.3% |
| Conclusion | This Product by Inspection Accords with the Enterprise Standard | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool, dry (≤25℃) and ventilated warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 43 - May cause sensitization by skin contact
Safety Description S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
WGK Germany 3
RTECS RC6308000
TSCA Yes
HS Code 2922491990
L-Norleucine (H-Nle-OH) (CAS: 327-57-1), is an isomer of leucine. A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally. As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis. Unusual amino acids, used in peptide synthesis, organic synthesis intermediates, pharmaceutical intermediates, biochemical reagents, chemical reagents.
Overview: Unnatural amino acids are the core intermediates of many drugs, especially new drugs in the past 10 years. The production processes of unnatural amino acids such as L-n-leucine mainly include asymmetric synthesis, chemical resolution and biological enzyme catalysis. Among them, asymmetric synthesis is not widely used in industrial production due to the relatively expensive chiral catalysts and chiral auxiliary reagents; chemical resolution is gradually not in line with the current requirements of clean production due to the large consumption of raw materials, large pollution, and low chiral content; bioenzyme catalysis has the advantages of high stereoselectivity, mild reaction conditions, high chiral content, product serialization, and less pollution. It is the development direction of non-natural amino acid industrial production technology in the future.