Commercial Supply Imatinib Mesylate and Related Intermediates:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8
| Chemical Name | 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride |
| Synonyms | Imatinib Mesylate Intermediate |
| CAS Number | 106261-49-8 |
| CAT Number | RF-PI229 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C13H20Cl2N2O2 |
| Molecular Weight | 307.22 |
| Melting Point | 305.0~307.0℃ |
| Solubility | Soluble in Water |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White to Almost White Powder to Crystal |
| Purity / Analysis Method | ≥98.0% (HPLC) |
| Loss on Drying | ≤0.50% |
| Residue on ignition | ≤0.50% |
| Total Impurities | ≤2.0% |
| Maximum Single Impurity | ≤1.0% |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediate of Imatinib Mesylate (CAS: 220127-57-1) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride (CAS: 106261-49-8) with high quality. It is an intermediate typically in the synthesis of Imatinib Mesylate (CAS: 220127-57-1). Imatinib Mesylate is a tyrosine kinase inhibitor, highly specific for BCR-ABL, an oral drug for the treatment of adult patients with Philadelphia chromosome positive chronic myeloid leukemia (CML) in the acute phase and certain forms of acute lymphoblastic leukemia (ALL), accelerated phase and chronic phase after failure of interferon therapy.