Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) with high quality. I-bu-rG Phosphoramidite is a modified building block commonly used in the solid-phase synthesis of RNA oligonucleotides.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase I-bu-rG Phosphoramidite or other products, please contact us by e-mail: alvin@ruifuchem.com
| Chemical Name | I-bu-rG Phosphoramidite |
| Synonyms | rG(ibu) Phosphoramidite; DMT-2′O-TBDMS-rG(ib) Phosphoramidite; 2'-TBDMS-rG(N-ibu)Phosphoramidite; 2'-TBDMS-ibu-G-CE-Phosphoramidite; 5'-O-DMT-2'-TBDMS-rG(N-iBu)-3'-CEDPA; N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-guanosine; 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite |
| Stock Status | In Stock |
| CAS Number | 147201-04-5 |
| Molecular Formula | C50H68N7O9PSi |
| Molecular Weight | 970.18 g/mol |
| Storage Temperature | Sealed in Dry, Store in Freezer, Under -20℃ Upon Receipt of the Product |
| Shipping Conditions | Shipped Under Ambient Temperature For Short Term |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories | RNA Phosphoramidites; Modified Nucleotides |
| Caution | Not For Human or Veterinary Use. For Research Use Only. |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White or Off-White Powder | White Powder |
| Solution Clarity Test | Clear | Clear |
| UV Spectrum | 200~350 nm, the maximum and minimum absorption wavelengths differ from the standard spectrum by +2nm |
Conforms |
| Water Content | ≤0.30% (Karl Fischer) | Conforms |
| Residual Solvent Content | ≤3.00% (GC) | Conforms |
| Single Impurity | ≤0.50% (HPLC) | Conforms |
| Purity / Analysis Method | ≥98.5% (HPLC) | 98.6% |
| Purity / Analysis Method | ≥98.5% (31P-NMR) | Conforms |
| 1H NMR Spectrum | Conforms to Structure | Conforms |
| LC-MS | Conforms to Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: 1g/10g/50g/100g/1kg/10kg/bulk. Amber glass screw cap vial or white plastic bottle.
Storage Condition: Keep the container tightly closed. Sealed in dry, store in freezer, under -20℃, under nitrogen. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
| WGK Germany | 3 |
| HS Code | 2934 9990.01 |
I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) is a modified building block commonly used in the solid-phase synthesis of RNA oligonucleotides. It is a guanosine nucleoside modified with a tert-butyldimethylsilyl (TBDMS) group protecting the 3'-OH group and an isobutyryl (ibu) group protecting the N2 position. The phosphoramidite group is attached to the 2'-OH position of the nucleoside.
I-bu-rG Phosphoramidite is used in the synthesis of oligonucleotides and nucleoside analogs for a variety of applications in biochemistry, molecular biology, and biotechnology.
I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) is used in the synthesis of nucleoside analogs and DNA/RNA oligonucleotides for a variety of applications in biochemistry, molecular biology, and biotechnology. It is used in the synthesis of modified DNA/RNA molecules for use in gene editing, gene therapy, and gene regulation. I-bu-rG Phosphoramidite is also used in the synthesis of modified nucleosides for use in drug discovery and development, as well as in the development of diagnostic assays.
I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) is a phosphoramidite monomer that is used in the synthesis of nucleoside analogs and DNA/RNA oligonucleotides. I-bu-rG Phosphoramidite is incorporated into the oligonucleotide chain during synthesis, and the 2-bromo-6-amino-4-nitrophenyl group at the 5’ position is used to modify the structure of the oligonucleotide. This modification can be used to alter the activity of the oligonucleotide or to target specific sequences.
I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) has been shown to have a variety of biochemical and physiological effects. It is used in the synthesis of modified DNA/RNA molecules for use in gene editing, gene therapy, and gene regulation. It has also been used in the synthesis of modified nucleosides for use in drug discovery and development, as well as in the development of diagnostic assays.
I-bu-rG Phosphoramidite (DMT-2′O-TBDMS-rG(ib) Phosphoramidite) (CAS: 147201-04-5) has several advantages and limitations for lab experiments. One advantage is that it is relatively easy to synthesize and can be used to modify the structure of DNA/RNA oligonucleotides. Additionally, it is inexpensive and can be used in a variety of applications. However, I-bu-rG Phosphoramidite has some limitations. For example, it is not as stable as other phosphoramidite monomers, and it can be difficult to deprotect.
There are several future directions for the use of I-bu-rG Phosphoramidite. It could be used to develop new nucleoside analogs for use in drug discovery and development. Additionally, I-bu-rG Phosphoramidite could be used to create modified DNA/RNA molecules for use in gene editing, gene therapy, and gene regulation. Finally, I-bu-rG Phosphoramidite could be used to develop new diagnostic assays for a variety of diseases. I-bu-rG phosphoramidite include expanding its therapeutic applications further, particularly in gene therapy and targeted drug delivery.