Manufacturer with High Purity and Stable Quality
Chemical Name: Naltrexone Hydrochloride
Synonyms: Naltrexone HCl
CAS: 16676-29-2
API High Quality, Commercial Production
| Chemical Name | Naltrexone Hydrochloride |
| Synonyms | Naltrexone HCl |
| CAS Number | 16676-29-2 |
| CAT Number | RF-API47 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C20H24ClNO4 |
| Molecular Weight | 377.86 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Almost White Crystalline Hygroscopic Powder |
| Infrared Absorption | Conform |
| Chlorides | Positive |
| Appearance of Solution | Clear |
| Acidity or Alkalinity | No more than 0.2ml of NaOH 0.02M or HCL 0.02M |
| Specific Rotation | -187° ~ -195° (calculated in the anhydrous basis) |
| Moisture (K.F) | ≤10.0% |
| Sulfated Ashes | ≤0.10% |
| Assay | 98.0%~102.0% (on anhydrous and solvent-free basis) |
| Related Substances | By Liquid Chromatography |
| Impurity A | ≤0.10% |
| Impurity B | ≤0.10% |
| Impurity C | ≤0.20% |
| Impurity D | ≤0.20% |
| Each Other Impurity | ≤0.10% |
| Total of Impurities | ≤1.0% |
| Heavy Metals | ≤10ppm |
| Residual Solvents Methanol | ≤ 2000ppm |
| Residual Solvents Acetone | ≤ 1000ppm |
| Test Standard | United States Pharmacopeia (USP) Standard |
| Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Naltrexone Hydrochloride (CAS: 16676-29-2), a non-selective opioid receptor antagonist; congener of naloxone. Naltrexone Hydrochloride (CAS: 16676-29-2) is a potent, long-acting, orally-effective narcotic antagonist useful in the management of narcotic addiction. Naltrexone hydrochloride is a pharmacodynamic blocker of exogenous opioids. Naltrexone hydrochloride was developed by DuPont in the United States and used in gradient detoxification programs to reduce the relapse rate of opiate-dependent patients after successful detoxification. Naltrexone hydrochloride is a new kind of morphine antagonist, which is used to treat opioid dependence and has obvious deaddiction effect. It plays an important role in the adjuvant therapy of preventing relapse of opioid dependence after deaddiction. Clinically, Naltrexone is mainly used to prevent opioid addicts from relapse after detoxification. It has the characteristics of effective oral administration, long acting time and no obvious toxic and side effects. In addition, naltrexone has been reported as an experimental clinical treatment for diseases related to the endogenous opioid system, such as alzheimer's disease, pediatric autism, alcohol dependence, chronic lung disease and obesity. Naltrexone hydrochloride is used in the treatment of alcohol and utilized for deceasing drinking habit. It is also used to prevent euphorigenic effects in the treatment of patients addicted to opioids.