Manufacturer with High Purity and Stable Quality
Commercial Supply Remdesivir and Related Intermediates
| Chemical Name |
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)tetrahydrofuran-2-Carbonitrile |
| Synonyms |
GS-441524; Remdesivir Metabolite; Remdesivir Intermediate; Nucleosid of Remdesivir; EVO984; Remdesivir O-Desphosphate Analogue; Remdesivir Related Compound 6 Impurity |
| CAS Number |
1191237-69-0 |
| CAT Number |
RF-PI298 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C12H13N5O4 |
| Molecular Weight |
291.26 |
| Solubility |
Solubled in DMSO |
| Storag |
Cool Dry Place |
| Shipping Condition |
Shipped Under Ambient Temperature |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Almost White Powder |
| Purity |
≥99.0% |
| Alpha-Isomer |
≤0.30% |
| O-Bn Derivative |
≤0.30% |
| N-Bn Derivative |
≤0.30% |
| Maximum Single Impurity |
≤0.30% |
| Loss on Drying |
≤1.0% |
| Residue on Ignition |
≤0.50% |
| Heavy Metals |
≤20ppm |
| Arsenic |
≤2ppm |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Remdesivir (CAS 1809249-37-3); COVID-19 |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats.