Manufacturer with High Purity and Stable Quality
Commercial Supply Tenofovir Related Intermediates
Tenofovir Disoproxil Fumarate CAS: 202138-50-9
Tenofovir CAS: 147127-20-6
(R)-Propylene Carbonate CAS: 16606-55-6
Adenine CAS: 73-24-5
| Name |
Tenofovir |
| Synonyms |
(R)-PMPA; (R)-9-(2-Phosphonomethoxypropyl)Adenine |
| CAS Number |
147127-20-6 |
| CAT Number |
RF-API07 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C9H14N5O4P |
| Molecular Weight |
287.22 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Almost White Crystalline Powder |
| Assay / Analysis Method |
98.0%~102.0% (on anhydrous basis) |
| Solubility |
Slightly Soluble in Water (0.1g in 100ml); Practically Insoluble in Methanol(0.01g in 100ml and over) |
| Sulphate Ash |
≤1.5% |
| Moisture (K.F) |
≤5.0% |
| Specification Optical Rotation |
-19.0° ~ -23.0° (at 25℃ anhydrous basis) |
| PMPA Monoester Impurity |
≤1.5% (HPLC) |
| Any Single Max Impurity |
≤0.5% (HPLC) |
| Total Impurities |
≤3.0% (HPLC) |
| Enantiomeric Purity |
≤0.5% (HPLC) |
| 9-propenyl adenine (HPLC) |
≤75ppm |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir disoproxil (Viread) is the first nucleotide analogue approved by the American FDA to treat HIV-1 infections. Tenofovir disoproxil is a drug used in the AIDS cocktail treatment method, and research shows that it has the ability to increase monkeys’ immunity to immunodeficiency viruses (similar to the human AIDS virus). Tenofovir disoproxil is used in combination with other reverse transcriptase inhibitors to treat HIV-1 infections and hepatitis B. Tenofovir is a drug used for the treatment of chronic heptatitis B as well as prevention and treatment of HIV/AIDS. It is a kind of nucleotide analog, acting as the reverse-transcriptase inhibitor (NtRTI). It inhibits the activity of HIV reverse transcriptase through competing with the natural substrate deoxyadenosine 5’-triphosphate, causing the termination of DNA chain.