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Ethyl 7-Chloro-2-Oxoheptanoate CAS 78834-75-0 Purity >98.0% (GC) Cilastatin Sodium Intermediate

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Ethyl 7-Chloro-2-Oxoheptanoate (CAS: 78834-75-0) with high quality, intermediate of Cilastatin Sodium (CAS: 81129-83-1). Imipenem and Cilastatin combination is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic.
Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Cilastatin Sodium intermediates, please contact us by e-mail: alvin@ruifuchem.com

Chemical Name Ethyl 7-Chloro-2-Oxoheptanoate 
Synonyms 7-Chloro-2-Oxoheptanoic Acid Ethyl Ester; ECO
Stock Status In Stock, Commercial Production  
CAS Number 78834-75-0
Molecular Formula C9H15ClO3
Molecular Weight 206.67 g/mol
Flash Point 113℃
Specific Gravity (20/20)  1.110 g/ml
Refractive Index n20/D 1.45
Store Under Inert Gas Store Under Inert Gas
Sensitive Air Sensitive, Heat Sensitive 
Storage Temperature Store Long-Term at 2-8℃
COA & MSDS Available
Origin of Product    Shanghai, China
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical
Items Specifications  Results
Appearance Pale Green to Light Yellow Transparent Liquid  Conforms        
Water by Karl Fischer  <0.50% 0.36%
Specific Gravity 1.105-1.110 Conforms  
Refractive Index n20/D 1.451-1.456 Conforms  
Purity / Analysis Method >98.0% (GC)  98.19%
1H NMR Spectrum Conforms to Structure   Conforms   
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Cilastatin Sodium (CAS: 81129-83-1)

Package: Fluorinated bottle, 25kg/drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery. 

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

HS Code  2918300090                                            

Ethyl 7-Chloro-2-Oxoheptanoate (CAS: 78834-75-0) has been used in the preparation of pharmaceuticals such as Cilastatin (CAS: 82009-34-5) and Cilastatin Sodium (CAS: 81129-83-1). Cilastatin has antibacterial effects on Gram-positive and negative aerobic and anaerobes. The antibacterial spectrum includes Streptococcus, Staphylococcus aureus, Escherichia coli, Klebsiella, some strains of Acinetobacter, Haemophilus bacillus, Proteus, Serratia, Pseudomonas aeruginosa, etc. Clinically, Cilastatin is mainly used for respiratory tract infections, biliary tract infections, urinary system and abdominal cavity infections, skin and soft tissues, bones and joints, gynecological infections caused by gram-positive bacteria, negative bacteria, and anaerobic bacteria.
Cilastatin was designed to inhibit renal metabolism of Imipenem and prolong its half-life. Formulations containing Cilastatin in combination with Imipenem have been used to treat susceptible bacterial infections.