Manufacturer with High Purity and Stable Quality
Chemical Name: Esmolol Hydrochloride
CAS: 81161-17-3
It is an ultra-short acting, cardioselective β-blocker with no intrinsic sympathomimetic activity.
| Chemical Name |
Esmolol Hydrochloride |
| Synonyms |
Esmolol HCl |
| CAS Number |
81161-17-3 |
| CAT Number |
RF-API35 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C16H26ClNO4 |
| Molecular Weight |
331.83 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Almost White Crystalline Powder |
| Identification (1) |
Should be positive reaction |
| Identification (2) |
Max. absorption should be at 222nm~274nm, Min. absorption should be at 245nm |
| Identification (3) |
The infrared spectrum of this product is consistent with that of the reference standard |
| Identification (4) |
The aqueous solution of the product gives reaction of chlorides |
| Melting Point |
85.0~92.0℃ |
| Clarity and Color of Solution |
Should be clarified or not thicker than No. 2 Turbidity standard liquid |
| pH |
2.5~4.5 |
| Loss on Drying |
≤0.5% |
| Sulfate |
≤0.030% |
| Residue on Ignition |
≤0.1% |
| Heavy Metals |
≤20ppm |
| Related Substances |
≤0.5% (HPLC) |
| Purity |
≥99.0% |
| Test Standard |
Enterprise Standard |
| Usage |
Pharmaceutical Intermediates; Organic Synthesis |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Esmolol Hydrochloride (CAS: 81161-17-3) with high quality.
Esmolol Hydrochloride is a cardioselective β-blocker, used to control rapid heartbeats or abnormal heart rhythms. Esmolol Hydrochloride is the hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation. Esmolol Hydrochloride has been used in the treatment of cardiac arrhythmias, postoperative hypertension, and acute ischemic heart disease, as well as to minimize myocardial contraction during cardiac surgery and attenuate the adrenergic response associated with tracheal intubation.