Manufacturer Supply Arabinonucleosides Intermediates with High Purity and Stable Quality
Vidarabine; Ara-A; CAS: 5536-17-4
Arabinofuranosyluracil; Ara-U; CAS: 3083-77-0
Cytarabine; Ara-C; CAS: 147-94-4
| Chemical Name |
Vidarabine |
| Synonyms |
Ara-A; Arabinoadenosine; Adenine 9-β-D-Arabinofuranoside; Vira-A |
| CAS Number |
5536-17-4 |
| CAT Number |
RF-PI220 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C10H13N5O4 |
| Molecular Weight |
267.25 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Off-White Crystalline Powder |
| Solubility |
Colorless Clear |
| Purity / Analysis Method |
≥99.0% (HPLC) |
| UV Content |
≥98% (on Dry Basis) |
| Specific Rotation [a]D20 |
-56.0°～-65.0° (C=1 in DMF) |
| Adenine |
≤0.50% |
| Adenosine |
≤0.50% |
| Ara-U |
≤0.50% |
| Melting Point |
260.0~265.0℃ |
| Test Standard |
Enterprise Standard |
| Storage Temperature |
Store at 0~8℃ |
| Usage |
API; Pharmaceutical Intermediates; Organic Synthesis |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Vidarabine (CAS: 5536-17-4), is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Vidarabine (CAS: 5536-17-4) is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine (CAS: 5536-17-4) is an inhibitor of A cyclase and DNA Polymerase. Adenine 9-beta-D-arabinofuranoside (ara-A) is a synthetically produced purine nucleoside that is used in cell signaling research. It has commonly been used in anti-viral research with hepadnaviridae and herpes simplex viruses. The nucleoside ara-A interferes with viral DNA synthesis, but only in its active phosphorylated form. Active ara-ATP inhibits synthesis by incorporating into viral DNA and preventing phosphodiester bridge formation.
Vidarabine (CAS: 5536-17-4) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus. Vidarabine (CAS: 5536-17-4) is capable of inhibiting acyclovir-resistant/TK-deficient mutants of HSV and VZV, because it is phosphorylated to its active vidarabine–triphosphate form by cellular kinases and is not dependent for its activation on the viral TK.