Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Daphnetin (CAS: 486-35-1) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com
| Chemical Name | Daphnetin |
| Synonyms | 7,8-Dihydroxycoumarin; Daphnetol; Ruixiangsu; 7,8-Dihydroxy-2H-1-Benzopyran-2-one |
| CAS Number | 486-35-1 |
| CAT Number | RF2868 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C9H6O4 |
| Molecular Weight | 178.14 |
| Melting Point | 256℃ |
| Solubility | Soluble in Methanol. Very Slightly Soluble in Benzene, Ether, Chloroform |
| HS Code | 29322090 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Pale Yellow Solid Powder |
| Purity / Analysis Method | >98.0% (HPLC) |
| Loss on Drying | <1.00% |
| Residue on Ignition | <0.30% |
| Total Impurities | <2.00% |
| Infrared Spectrum | Conforms to Structure |
| 1 H NMR Spectrum | Conforms to Structure |
| Test Standard | Enterprise Standard |
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Daphnetin (CAS: 486-35-1) is a natural coumarin derivative, is a protein kinase inhibitor; inhibits EGFR, PKA and PKC; exhibits anti-inflammatory and anti-oxidant activities. Daphnetin, mainly extracted from Yu Ruixiang Changbai Daphne (Daphne Korean Nakai), Daphne giraldii Nitsche bark, and root bark, is the main efficacy component of the plants D.tangutica Maxim and D.retttsa Hemsl. Changbai daphnes has the pharmacological effects of warming the spleen and stomach, relaxing the muscles and joints, and promoting circulation. In TCM, it’s commonly used as medicines for treatment of injuries. Because Changbai daphne is a pungent and warm natured herbal medicine, it was used to warm the spleen and stomach by dispelling cold. From then on artificially synthesized Daphnetin has been successfully implemented. A large-scale industrial production can be acquired. The followup researches on the metabolism and pharmacological activity of daphnetin were carried out. In 2009, the State Food and Drug Administration of China approved daphnetin capsule to be used in the clinical. It has been verified by a large number of clinical cases that oral daphnetin capsule can significantly improve thromboangiitis obliterans; oral daphnetin has a better curative effect than intramuscular injection of Changbai daphne in patients with angina pectoris due to coronary heart disease. Daphnetin shows an obvious analgesic sedative effect on surgical and nonsurgical pain-relieved patients after intravenous drip or injection of daphnetin; oral daphnetin capsule shows significant therapeutic effects on rheumatoid arthritis.