Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of D-Tyrosine (H-D-Tyr-OH) (CAS: 556-02-5) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase D-Tyrosine, Please contact: alvin@ruifuchem.com
Chemical Name |
D-Tyrosine |
Synonyms |
H-D-Tyr-OH; D(+)-Tyrosine; Dextro-Tyrosine; (R)-2-Amino-3-(4-Hydroxyphenyl)propionic Acid; 3-(4-Hydroxyphenyl)-D-Alanine |
Stock Status |
In Stock, Production Capacity 30 Tons per Month |
CAS Number |
556-02-5 |
Molecular Formula |
C9H11NO3 |
Molecular Weight |
181.19 g/mol |
Melting Point |
310.0~314.0℃ |
Density |
1.333 |
Water Solubility |
Soluble in Water |
Solubility (5% in 1 M HCl) |
Clear Colorless to Almost Colorless to Yellow |
Storage Temp. |
Cool & Dry Place (2~8℃) |
COA & MSDS |
Available |
Category |
Amino Acids and Derivatives |
Brand |
Ruifu Chemical |
Items |
Inspection Standards |
Results |
Appearance |
White Crystals or Crystalline Powder |
Complies |
Specific Rotation [α]20/D |
+10.5° to +11.5° (C=5 in 1N HCl) |
+10.9° |
State of Solution (Transmittance) |
Clear and Colorless ≥95.0% |
98.5% |
Ammonium (NH4) |
≤0.02% |
<0.02% |
Sulfate (SO4) |
≤0.03% |
<0.03% |
Chloride (Cl) |
≤0.03% |
<0.03% |
Iron (Fe) |
≤20ppm |
<20ppm |
Heavy Metals (Pb) |
≤10ppm |
<10ppm |
Arsenic (As2O3) |
≤2ppm |
<1ppm |
Other Amino Acids |
Not Detectable by TLC |
Complies |
Loss on Drying |
<0.20% |
0.15% |
Residue on Ignition (Sulfated) |
<0.20% |
0.10% |
Assay |
98.5%~101.0% |
100.7% |
Chiral Purity |
<0.50%, L-Enantiomer |
Complies |
pH |
5.0 to 6.5 |
5.8 |
IR Spectrum |
In Accordance With the Standard |
Complies |
Conclusion |
The product has been tested & complies with the AJI92 Standard |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
TSCA Yes
HS Code 2922491990
D-Tyrosine (H-D-Tyr-OH) (CAS: 556-02-5), amino acids and derivatives, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, food / feed additives, nutritional supplement, biochemical reagent or chemical reagent.
D-Tyrosine is the D-form amino acid of Tyrosine. It is a non-essential amino acid. In animals, it can be de novo synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid, hormones and melanin. Specially, study has shown that it can be taken s a chiral precusor to potent inhibitors of human Nonpancreatic secretory phospholipase A 2(IIa) with strong anti-inflammatory activity. It can also be used as a starting material for the preparation of anisomycin.
D-Tyrosine is a non-protein source of chiral amino acids, which is widely used in the synthesis of chiral drugs. For example, the peptide drug atosiban synthesized with D-Tyrosine as a chiral intermediate is a tocolytic drug, and the synthesized deacetylated anisomycin has antigenic, anti-Amoeba, anti-fungal, anti-swelling, to prevent the role of plant fungal disease, synthetic peptide drugs for the treatment of malignant tumors with special efficacy, can also be used for the lungs, central nervous system, joints, endocardium, eyes, ears, skin, gastrointestinal, urinary system inflammation with excellent efficacy of anti-inflammatory drugs.
Production method with DL-Tyrosine as raw material, acylation reaction with Chloroacetyl Chloride was carried out, filtered and concentrated, the product was extracted with boiling acetone, recrystallized from petroleum ether, and recrystallized again after acidification with hydrochloric acid.