Ruifu Chemical is the leading manufacturer of D-4-Hydroxyphenylglycine (H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine) (CAS: 22818-40-2) with high quality, production capacity 4000 tons per year. Mainly used in the production of semisynthetic β-lactam antibiotics, such as Penicillin, Amoxicillin, and Cefadroxil, Cephalosporins. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase D-4-Hydroxyphenylglycine, Please contact: alvin@ruifuchem.com
| Chemical Name | D-4-Hydroxyphenylglycine |
| Synonyms | H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine; 4-Hydroxy-D-(-)-2-Phenylglycine; D-(-)-4-Hydroxyphenylglycine; D-p-Hydroxyphenylglycine; D-(-)-2-(4-Hydroxyphenyl)glycine; D-(-)-2-(p-Hydroxyphenyl)glycine; (R)-(-)-2-Amino-2-(4-Hydroxyphenyl)acetic Acid; D-(-)-α-(4-Hydroxyphenyl)glycine; D-(-)-α-Amino-4-Hydroxyphenylacetic Acid; D-α-p-Hydroxyphenylglycine |
| Impurity | Cefadroxil EP Impurity A; Amoxicillin EP Impurity A |
| Stock Status | In Stock, Production Capacity 4000 Tons per Year |
| CAS Number | 22818-40-2 |
| Molecular Formula | C8H9NO3 |
| Molecular Weight | 167.16 g/mol |
| Melting Point | 238.0~241.0℃(dec.)(lit.) |
| Density | 1.396 g/cm3 at 20℃ |
| Solubility in 1mol/L HCl | Almost Transparency |
| COA & MSDS | Available |
| Origin of Product | China |
| Product Categories |
Pharmaceutical Intermediates; Unusual Amino Acids |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White or Off-White Crystalline Powder | Complies |
| Specific Rotation [a]20/D | -155.0° ~ -161.0° (C=1 in 1M HCl) | -156.1° |
| Water by Karl Fischer | <0.50% | 0.12% |
| Assay / Analysis Method |
>99.0% (Titration) | 99.3% |
| Purity / Analysis Method | >99.0% (HPLC) | >99.0% |
| Infrared Spectrum | Consistent with Structure | Complies |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg paper bag with double-layer PE inner bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture. Incompatible with oxidizing agents.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
TSCA Yes
HS Code 2922501000
D-4-Hydroxyphenylglycine (H-D-Phg(4-OH)-OH; 4-Hydroxy-D-Phenylglycine) (CAS: 22818-40-2) is used as pharmaceutical intermediates, is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Penicillin (CAS: 69-57-8), Amoxicillin (CAS: 26787-78-0) and Cefadroxil (CAS: 66592-87-8), Cephalosporins and other pharmaceutical synthesis.