Ruifu Chemical Supply Prostaglandin Intermediates:
(-)-Corey Lactone Diol CAS 32233-40-2
(+)-Corey Lactone Diol CAS 76704-05-7
(±)-Corey Lactone Diol CAS 54423-47-1
(-)-Corey Lactone Benzoate CAS 39746-00-4
(-)-Corey Lactone 4-Phenylbenzoate Alcohol; BPCOD CAS 31752-99-5
| Chemical Name |
(-)-Corey Lactone 4-Phenylbenzoate Alcohol |
| Synonyms |
(-)-Corey Lactone 4-Phenylbenzoate; (-)-Corey lactone 4-PBP; BPCOD; (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(Hydroxymethyl)-2-oxo-2H-Cyclopenta[b]furan-5-yl 1,1′-Biphenyl-4-Carboxylate; (3aR,4S,5R,6aS)-Hexahydro-4-Hydroxymethyl-5-(4-Phenylbenzoyloxy)cyclopenta[b]furan-2-one |
| CAS Number |
31752-99-5 |
| CAT Number |
RF-PI1998 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C21H20O5 |
| Molecular Weight |
352.38 |
| Density |
1.30±0.10 g/cm3 |
| Water Solubility |
H2O: Insoluble |
| Solubility |
Soluble in Chloroform and Methanol |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White to Yellowish Powder or Crystalline Powder |
| Identification by HPLC |
The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard as obtained in the isomer |
| Melting Point |
128.0~134.0℃ |
| Purity / Analysis Method |
>99.0% (HPLC) |
| Water Content (K.F) |
<0.50% |
| Residue on Ignition |
<0.20% |
| Specific Rotation [α]20/D |
-85.0° to -89.0° (C=1.0, CHCl3) |
| (+) Isomer |
<0.10% |
| Maximum Single Impurity |
<0.50% |
| Total Impurities |
<1.00% |
| Infrared Spectrum |
Conforms to Structure |
| Proton NMR Spectrum |
Conforms to Structure |
| Test Standard |
Enterprise Standard |
| Usage |
Prostaglandin Intermediates; Latanoprost Intermediate |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
(-)-Corey Lactone 4-Phenylbenzoate Alcohol (CAS: 31752-99-5) is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α. Used in Prostaglandin Derivatives; Used as Prostaglandin Series Intermediates. Prostaglandins are a kind of important endogenous physiological active substances and important mediators of various physiological processes, with high pharmacological activity. Clinically, Prostaglandins are all synthesized artificially. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α. (-)-Corey Lactone 4-Phenylbenzoate Alcohol is an intermediate of Latanoprost (CAS: 130209-82-4). Latanoprost is a prostaglandin F2a analogue. It is a prostanoid selective FP receptor agonist that is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor. It is used to treat certain kinds of glaucoma(open-angle glaucoma ocular hypertension). It is also used to treat a condition called hypertension of the eye. Latanoprost is used to increase the natural outflow of fluid (aqueous humor) from inside the eye into the bloodstream. It appears to work by increasing the outflow of fluid from the eye. This lowers the pressure in the eye.