Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 4-Pyridylboronic Acid
CAS: 1692-15-5
Chemical Name |
4-Pyridylboronic Acid |
Synonyms |
Pyridine-4-Boronic Acid |
CAS Number |
1692-15-5 |
CAT Number |
RF-PI571 |
Stock Status |
In Stock, Production Scale Up to Tons |
Molecular Formula |
C5H6BNO2 |
Molecular Weight |
122.92 |
Solubility |
Insoluble in Water |
Melting Point |
>300℃ (lit.) |
Brand |
Ruifu Chemical |
Item |
Specifications |
Appearance |
White Powder |
Moisture (K.F) |
≤0.50% |
Purity / Analysis Method |
≥99.0% (HPLC) |
Single Impurity |
≤0.50% |
Total Impurities |
≤1.0% |
Test Standard |
Enterprise Standard |
Usage |
Pharmaceutical Intermediates |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
4-Pyridylboronic Acid (CAS: 1692-15-5) can be used as a candidate for Suzuki-Miyaura coupling reaction. Especially, as a N-containing building blocks, pyridine-4-boronic acid was employed to construct some heterocyclic compounds with superior biological activities. 4-Pyridylboronic Acid is a kind of boronic acid derivative. It is useful building blocks in crystal engineering. It can also be used as a catalyst to act as a dehydrative condensation agent to synthesize amides using carboxylic acid and amines as raw materials. Its derivative, polystyrene-bound 4-pyridineboronic acid, is a useful catalyst for amidation reaction and esterification of alpha-hydrocarboxylic acids.
Reagent used for: Palladium-catalyzed Suzuki-Miyaura coupling reactions; Ligand-free palladium-catalyzed Suzuki coupling reaction under microwave irradation; Reagent used in: Preparation of HIV-1 protease inhibitors; Potential cancer threapeutics, such as PDK1 and protein kinase CK2 inhibitors.