Ruifu Chemical is the leading manufacturer of Tetrabutylammonium Fluoride Hydrate (TBAF Hydrate) (CAS: 429-41-4) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase TBAF Hydrate, Please contact: alvin@ruifuchem.com
| Chemical Name |
Tetrabutylammonium Fluoride Hydrate |
| Synonyms |
TBAF Hydrate |
| Stock Status |
In Stock, Commercial Scale |
| CAS Number |
429-41-4 |
| Molecular Formula |
[CH3(CH2)3]4NF·xH2O |
| Molecular Weight |
261.46 (Anhydrous Basis) |
| Melting Point |
62.0~63.0℃(lit.) |
| Flash Point |
-17℃(1°F) |
| Density |
0.953 g/mL at 25℃ |
| Refractive Index n20/D |
1.456 |
| Sensitive |
Hygroscopic. Easy to Moisture Absorption |
| Solubility in Water |
Completely Miscible in Water |
| Solubility |
Miscible with Terahydrofuran, Acetonitrile, Dimethyl Sulfoxide and Organic Solvents |
| COA & MSDS |
Available |
| Product Categories |
Quaternary Ammonium Salts |
| Brand |
Ruifu Chemical |
| Items |
Inspection Standards |
Results |
| Appearance |
White Solid |
White Solid |
| Water by Karl Fischer |
≤18.0% |
Complies |
| TBHF-HF (Neutralization Titration) |
≤2.0% |
<2.0% |
| Assay / Analysis Method |
≥98.0% (Titration by HClO4) |
99.3% |
| Infrared Spectrum |
Conforms to Structure |
Complies |
| Proton NMR Spectrum |
Conforms to Structure |
Complies |
| Conclusion |
The product has been tested & complies with the specifications |
Package: Bottle, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with oxidizing agents and oxygen.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R34 - Causes burns
R19 - May form explosive peroxides
R11 - Highly Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
R40 - Limited evidence of a carcinogenic effect
R37 - Irritating to the respiratory system
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S33 - Take precautionary measures against static discharges.
S29 - Do not empty into drains.
S16 - Keep away from sources of ignition.
S36 - Wear suitable protective clothing.
UN IDs UN 3261 8/PG 2
WGK Germany 3
FLUKA BRAND F CODES 3
TSCA Yes
HS Code 2923900090
Hazard Note Flammable/Irritant
Hazard Class 3
Packing Group II
Tetrabutylammonium Fluoride Hydrate (TBAF Hydrate) (CAS: 429-41-4), is a fluoride salt and a tetrabutylammonium salt. It has a role as a phase-transfer catalyst.
Catalyst for etherification of alcohols and phenols with alkyl halides Catalyst for benzylation reactions.
TBAF Hydrate is a reagent in organic syntheses in addition, condensation, base-catalyzed cyclization reactions, fluorination and desulfonylation reactions and as a deprotecting agent. Typically dried prior to use.
Tetrabutylammonium Fluoride is widely used in the field of organic synthesis and can be used as fluorination reagent, silylation catalyst for alcohols, phase transfer catalyst, etc.
Tetrabutylammonium Fluoride is used as a fluorinating agent and silylation catalyst for alcohols in organic synthesis, and as a basic reagent in alkylation and hydroxylation reactions. Good cationic phase transfer catalyst. Catalysts for acylation, silicification and silicification
Tetrabutylammonium Fluoride is a commonly used organic soluble fluoride salt. It is used as a base, a phase transfer catalyst, and as a fluoride source. In the research field of fluoride sensor development, TBAF is used as an easy to handle and measurable fluoride anion source. The fluoride in TBAF, once dissolved, can be thought of as a free fluoride with little interaction with the ammonium cation. Since TBAF should not absorb light at wavelengths greater than 240nm, it is useful to monitor sensing reactions with visible spectroscopy.
Since the fluorine atom in tetrabutylammonium fluoride is a strong hydrogen bond acceptor, it is very easy to absorb moisture, so the product is usually Tetrabutylammonium fluoride trihydrate or Tetrabutylammonium fluoride tetrahydrofuran solution is sold. When it is heated to 77℃ under vacuum, the compound will decompose into hydrogen fluoride salt. When the sample is dried at 40℃ under high vacuum, it will still get 10-30 mol% water content and 10% difluoride salt.