Ruifu Chemical is the leading manufacturer of 1-(6-Methylpyridin-3-yl)-2-[4-(Methylthio)phenyl]ethanone (CAS: 221615-72-1) with high quality, an important intermediate of Etoricoxib (CAS: 202409-33-4).
Etoricoxib is widely used in the treatment of osteoarthritis (OA), acute gouty arthritis, and other diseases.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Etoricoxib intermediates, Please contact: alvin@ruifuchem.com
| Chemical Name | 1-(6-Methylpyridin-3-yl)-2-[4-(Methylthio)phenyl]ethanone |
| Synonyms | Etoricoxib Intermediate 1; Etoricoxib Impurity P; 1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethan-1-one; 1-(6-Methylpyridin-3-yl)-2-[4-(Methylsulfanyl)phenyl]ethanone |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 221615-72-1 |
| Molecular Formula | C15H15NOS |
| Molecular Weight | 257.35 g/mol |
| Melting Point | 111.0~113.0℃ |
| Density | 1.17±0.10 g/cm3 |
| Store Under Inert Gas | Store Under Inert Gas (Nitrogen or Argon) at 2~8℃ |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White to Cream to Light Yellow Powder | Off-White Powder |
| Loss on Drying | <1.00% | 0.16% |
| Residue on Ignition | <0.50% | 0.08% |
| Heavy Metals (Pb) | <20ppm | <20ppm |
| Purity / Analysis Method | >98.0% (HPLC) | 98.5% |
| Infrared Spectrum | Consistent with Structure | Complies |
| NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Intermediate of Etoricoxib (CAS: 202409-33-4) | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
1-(6-Methylpyridin-3-yl)-2-[4-(Methylthio)phenyl]ethanone (CAS: 221615-72-1) is used as an intermediate of Etoricoxib (CAS: 202409-33-4). Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is a selective cyclooxygenase-2 (COX-2) inhibitor, meaning it inhibits the enzyme responsible for the production of prostaglandins, which are involved in the body’s inflammatory response. Etoricoxib is used to treat a variety of conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used to reduce pain, fever, and swelling associated with acute gout.