Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-Hydrazinobenzenesulfonamide Hydrochloride (CAS: 17852-52-7) with high quality, intermediate of Celecoxib (CAS: 169590-42-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Celecoxib Intermediates, Please contact: alvin@ruifuchem.com
| Celecoxib |
CAS 169590-42-5 |
| 4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione |
CAS 720-94-5 |
| 4-Hydrazinobenzenesulfonamide Hydrochloride |
CAS 17852-52-7 |
| Ethyl Trifluoroacetate |
CAS 383-63-1 |
| Chemical Name |
4-Hydrazinobenzenesulfonamide Hydrochloride |
| Synonyms |
4-SPH; 4-SAPH.HCl; 4-Hydrazinobenzene-1-Sulfonamide Hydrochloride; 4-Sulfonamidophenylhydrazine Hydrochloride; 4-Sulfonamidephenylhydrazine HCl; (4-Sulfamoylphenyl)hydrazine Hydrochloride |
| Stock Status |
In Stock, Commercial Production |
| CAS Number |
17852-52-7 |
| Molecular Formula |
C6H9N3O2S·HCl |
| Molecular Weight |
223.68 g/mol |
| Melting Point |
210.0~ 213.0℃(lit.) |
| Density |
1.644 (at 20℃) |
| Sensitive |
Hygroscopic |
| Water Solubility |
Soluble in Water |
| COA & MSDS |
Available |
| Sample |
Available |
| Origin |
Shanghai, China |
| Brand |
Ruifu Chemical |
| Items |
Inspection Standards |
Results |
| Appearance |
Light Yellow to Pale Brown Powder |
Complies |
| Melting Point |
210.0~ 213.0℃ |
211.2℃ |
| Loss on Drying |
<1.00% |
0.25% |
| Ash Content |
<0.50% |
0.11% |
| Single Impurity |
<0.50% |
Complies |
| Total Impurities |
<2.00% |
0.51% |
| Heavy Metals (Pb) |
≤20ppm |
<10ppm |
| Purity / Analysis Method |
>98.0% (HPLC) |
99.49% |
| 1H NMR Spectrum |
Consistent with Structure |
Complies |
| Conclusion |
The product has been tested and complies with the given specifications |
| Application |
Intermediate of Celecoxib (CAS: 169590-42-5) |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Store away from oxidizing agents, water/moisture and bases. Keep away from sunshine; avoid fire.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
| Risk Codes |
R22 - Harmful if swallowed |
| R36/37/38 - Irritating to eyes, respiratory system and skin |
| Safety Description |
S36 - Wear suitable protective clothing |
| S24/25 - Avoid contact with skin and eyes |
| WGK Germany |
3 |
| RTECS |
DA9380000 |
| HS Code |
2935900090 |
| Hazard Note |
Irritant |
4-Hydrazinobenzenesulfonamide Hydrochloride (CAS: 17852-52-7), pharmaceutical intermediate, mainly used in the production of Celecoxib (CAS: 169590-42-5). Celecoxib and Rofecoxib are two specific inhibitors of cyclooxygenase-2 (COX-2) commonly used in clinic at present. They were successfully developed by GD Searle & Pfizer company in the United States and went on sale in 1999, their trade names: Celebrex. Celebrex, this product has significant analgesic and anti-inflammatory effects, and the incidence of upper gastrointestinal ulcers and other complications is the lowest. Celecoxib is a non-steroidal anti-inflammatory drug, which exerts anti-inflammatory and analgesic effects by inhibiting COX-2 to block the synthesis of prostaglandins from arachidonic acid. It is clinically suitable for the treatment of acute and chronic osteoarthritis and rheumatoid arthritis.