Gatifloxacin CAS 112811-59-3 Purity >99.0% (HPLC)

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Gatifloxacin (CAS: 112811-59-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Gatifloxacin and intermediates , Please contact: alvin@ruifuchem.com

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture, avoid fire and heat.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

P260: Do not breathe dust/fume/gas/mist/vapours/spray
P280: Wear protective gloves/protective clothing/eye protection/face protection
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do, continue rinsing

Gatifloxacin (CAS: 112811-59-3) is an antibiotic of the fourth-generation fluoroquinolone family,that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
Gatifloxacin is used to treat a variety of bacterial infections. It works by stopping the growth of bacteria.
This medication belongs to a class of drugs called quinolone antibiotics.
This antibiotic only treats bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness .
Gatifloxacin is a novel orally-active fluoroquinolone antibiotic with a potent and broad spectrum of activity against gram-positive (S.pneumonia, S.aureus) and gram-negative bacteria. It shows good activity against strains resistant to established antituberculosis agents. Gatifloxacin was marketed for the treatment of respiratory tract and urinary infections, particularly the treatment of certain community-acquired infections (such as bronchitis, pneumonia and common sexually-transmitted diseases). Comparative studies with ciprofloxacin, ofloxacin and sparfloxacin against fluoroquinolone-resistant organisms indicated a better or equivalent effectiveness with less phototoxic adverse effects.  

Gatifloxacin sold under the brand names Gatiflo, Tequin and Zymar, is an antibiotic of the fourth-generation fluoroquinolone family,[1] that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Bristol-Myers Squibb introduced Gatifloxacin in 1999 under the proprietary name Tequin for the treatment of respiratory tract infections, having licensed the medication from Kyorin Pharmaceutical Company of Japan. Allergan produces it in eye-drop formulation under the names Zymar and Zymaxid. In many countries, gatifloxacin is also available as tablets and in various aqueous solutions for intravenous therapy.  

1 Antibacterial spectrum:In addition to the gram negative bacteria and gram positive bacteria have a strong antibacterial activity, the anaerobic bacteria, bacteria, mycoplasma, chlamydia and Mycobacterium, also have a good antibacterial effect.
2 Blood drug concentration is high, widely distributed in the body, with a long half-life, absolute bioavailability, strong bactericidal power.
3 Anti infection index is the highest in the quinolones have been listed
4 Stable chemical properties, small toxic side effect, not easy to produce drug resistance. 

Gatifloxacin is currently available in the US and Canada only as an ophthalmic solution. In China it is sold in tablet as well as in eye drop formulations.Ophthalmic anti-infectives are generally well tolerated. The concentration of the drug observed following oral administration of 400 mg gatifloxacin systemically is approximately 800 times higher than that of the 0.5% Gatifloxacin eye drop. Given as an eye drop, Gatifloxacin Ophthalmic Solution 0.3% & 0.5% cause very low systemic exposures. Therefore, the systemic exposures resulting from the gatifloxacin ophthalmic solution are not likely to pose any risk for systemic toxicities.