Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) with high quality. Ruifu can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Carvedilol Phosphate Hemihydrate, Please contact: alvin@ruifuchem.com
Related Intermediates of Carvedilol
Chemical Name | Carvedilol Phosphate Hemihydrate |
Synonyms | BM 14190 Phosphate Hemihydrate; 1-(9H-Carbazol-4-yloxy)-3-[2-(2-Methoxyphenoxy)ethylamino]propan-2-olphosphoricacidhydrate |
Stock Status | In Stock |
CAS Number | 610309-89-2 |
Molecular Formula | C24H26N2O4.H3PO4.0.5H2O |
Molecular Weight | 513.47 g/mol |
COA & MSDS | Available |
Brand | Ruifu Chemical |
Items | Inspection Standards | Results |
Appearance | White Crystalline Powder | Complies |
Water by Karl Fischer | ≤2.50% | Complies |
Related Substances | ≤0.50% | Complies |
Heavy Metals (Pb) | ≤10ppm | <10ppm |
Purity / Analysis Method | >99.0% (HPLC) | 99.5% |
Infrared Spectrum | Conforms to Structure | Complies |
Conclusion | The product has been tested & complies with the specifications |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in a tightly closed container. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Carvedilol Phosphate Hemihydrate (CAS: 610309-89-2) is a selective blocking α1-receptor and non-selective β-receptor blocker, no intrinsic Sympathimetic active drugs, bioavailability of 10 ~ 47%, not affected by food, the effect on α1-receptor is significantly lower than β1-and β2-receptor, the intensity ratio of β 1-and β 2-receptor blockade is 1:10~1:100. The effect of β 1-receptor blockade is about 1/2 of labetalol, and its α1 blockade is weaker than prazosin. It can dilate blood vessels, reduce peripheral vascular resistance, dilate coronary and renal vessels, and reduce pulmonary wedge pressure. It has obvious protective effect on myocardial hypoxia and myocardial injury caused by myocardial infarction, which may be related to blocking β-receptor, which can reduce the decrease of myocardial glycogen and the increase of pH, and reduce the infarct size.
Carvedilol Phosphate Hemihydrate is used to treat mild to moderate hypertension and can be used alone or in combination with other antihypertensive drugs (especially thiazide diuretics). For symptomatic chronic congestive heart failure.
Carvedilol Phosphate Hemihydrate is a non-selective β/α-1 receptor blocker. Carvedilol inhibit lipid peroxidation with an IC50 of 5 μM. Carvedilol is a multi-purpose antihypertensive agent with potential for the study of angina pectoris and congestive heart failure.