Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Calcium Dobesilate Monohydrate (CAS: 20123-80-2) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Calcium Dobesilate Monohydrate, Please contact: alvin@ruifuchem.com
| Chemical Name | Calcium Dobesilate Monohydrate |
| Synonyms | Calcium Dobesilate; Calcium 2,5-Dihydroxybenzenesulfonate; 2,5-Dihydroxybenzenesulfonic Acid Calcium Salt; Dexium |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 20123-80-2 |
| Molecular Formula | C12H10CaO10S2·xH2O |
| Molecular Weight | 436.43 (418.40 as Anhydrous) |
| Melting Point | >300℃(dec) |
| Sensitive | Hygroscopic |
| Solubility | Soluble in Water, 15mg/ml, Clear |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
API (Active Pharmaceutical Ingredient) |
| Caution | Not Intended for Human Use. For Research Use Only. |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White or Almost White, Hygroscopic Powder | White Hygroscopic Powder |
| Identification | A. The solution shows two absorption maxima, at 221nm and 301nm |
Conforms |
| B. A blue colour and a precipitate are immediately produced |
Conforms | |
| C. 2ml of freshly prepared solution S gives reaction of calcium |
Conforms | |
| Solubility | Solubility Water: Very Soluble Ethanol: Soluble Isopropanol: Very Slightly Soluble Methylene Chloride: Practically Insoluble |
Pass |
| pH | 4.5~6.0 | 4.6 |
| Appearance of Solution | Solution S, when freshly prepared, is clear and colourless |
Conforms |
| Hydroquinone | <0.10% (HPLC Area) | 0.05% |
| Iron (Fe) | <10ppm | <10ppm |
| Heavy Metals (Pb) | <10ppm | <10ppm |
| Water by Karl Fischer | 4.0%~6.0% | 5.1% |
| Residual Solvents | (Alcohol)<0.10% | 0.08% |
| Assay | 99.0%~102.0% (Calculated on the Anhydrous Basis) |
99.9% |
| Infrared Spectrum | Consistent with Structure | Complies |
| Conclusion | This product by inspection accords with the BP2009/EP6 Standard | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
Hazard Class IRRITANT
Calcium Dobesilate Monohydrate (CAS: 20123-80-2) is a vasoprotective. It is the calcium salt of dobesilic acid. It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
Calcium Dobesilate is an antioxidant that has been used to treat diabetic retinopathy, in which it slows progression of the disease during long-term oral treatment by reducing microvascular permeability, leading to improved visual acuity. It not only acts as an antioxidant but also stimulates endothelial production of nitric oxide.