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Chemical Name |
2-Amino-3,5-Dibromobenzaldehyde |
Synonyms |
3,5-Dibromoanthranilaldehyde; Ambroxol EP Impurity E |
CAS Number |
50910-55-9 |
CAT Number |
RF-PI338 |
Stock Status |
In Stock, Production Scale Up to Tons |
Molecular Formula |
C7H5Br2NO |
Molecular Weight |
278.93 |
Brand |
Ruifu Chemical |
Item |
Specifications |
Appearance |
Yellow Powder |
Assay / Analysis Method |
≥99.0% (HPLC) |
Melting Point |
136.0~140.0℃ |
Clarity |
Conforms |
Loss on Drying |
≤0.50% |
Impurity A |
≤0.50% (2-Amino-3,5-Dibromo-Benzaldehyde) |
Impurity B |
≤0.10% (2-Amino-3,5-Dibromobenzoic Acid Methyl Ester) |
Mono-Bromide |
≤0.10% |
Any Unknown Impurity |
≤0.10% |
Total Impurities |
≤1.0% |
Test Standard |
Enterprise Standard |
Usage |
Intermediate of Ambroxol Hydrochloride (CAS 23828-92-4) Expectorant |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.
2-Amino-3,5-Dibromobenzaldehyde (CAS: 50910-55-9), also named 3,5-Dibromoanthranilaldehyde, is an important pharmaceutical intermediate in the synthesis of Ambroxol Hydrochloride (CAS 23828-92-4). Ambroxol Hydrochloride is a new generation of sputum dissolving agent, it can improve the expectoration, and has effect on promoting the secretion of the lung surfactant and airway as well as the ciliary movement. Ambroxol Hydrochloride can be clinically widely applied to the acute and chronic respiratory disorders accompanied with abnormal secretion of respiratory tract, especially to the expectorant treatment of chronic bronchitis, respiratory distress syndrome of newborns and the adjuvant therapy of the lung surgery. It has advantages such as low toxicity, accurate efficacy and excellent synergistic effect when being used together with antibiotics. All the above points make it be a common expectorant.