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Azilsartan CAS 147403-03-0 Purity >99.5% (HPLC) API Factory

Manufacturer Supply, High Purity, Commercial Production  

Chemical Name Azilsartan
Synonyms 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-Carboxylic Acid
CAS Number 147403-03-0
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C25H20N4O5
Molecular Weight 456.46
Melting Point 188℃ (dec.)
Density 1.42
Brand Ruifu Chemical
Item Specifications
Appearance White or Off-White Crystalline Powder 
Identification Correspond to Reference Standard
Solubility Practically Insoluble in Water, Slightly Soluble in Ethanol
Purity / Analysis Method  >99.5% (HPLC)
Loss on Drying <0.50%
Residue on Ignition <0.20%
Heavy Metals <10ppm
Related Substances
Impurity A <0.15%
Impurity B  <0.10%
Impurity C <0.10%
Other Unknown Largest Single Impurity <0.10%
Total Impurities <0.50%
Residual Solvents
Dichloromethane <0.06%
Acetone  <0.50%
Ethyl Acetate <0.50%
Methanol <0.30%
Test Standard Enterprise Standard
Usage API

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Azilsartan (CAS: 147403-03-0) is an angiotensin II receptor antagonist drug under development for the treatment of hypertension, which is mostly used for the treatment of hypertension. It is also the only angiotensin II receptor antagonist (sartan class) drug in the advanced clinical stage at present. Azilsartan and Chlorthalidone combination is used to treat high blood pressure (hypertension). Azilsartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, azilsartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Azilsartan was approved and launched in Japan for the treatment of arterial hypertension in May 2012. Azilsartan, which is marketed under the trade name Azilva. 


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